Dimyristoyl phosphatidyl ethanolamine,

Recently, the competitive adsorption dynamics of phospholipid/protein mixed system at the chloroform/water interface was investigated by using the drop volume technique. The three proteins P-Lactoglobulin, P-Casein, and Human Serum Albumin were used in this study. To investigate the influence of the phospholipid structure at concentrations close to the CAC (critic aggregation concentration) the four lipids dipalmitoyl phosphatidyl choline (DPPC), dimyristoyl phosphatidyl choline (DMPC), dimyristoyl phosphatidyl ethanolamine (DMPE)... 

The total lasalocid-membrane binding reaction is a very sensitive fimction of the membrane polar head group composition Incorporation of dimyristoyl phosphati-dic acid (DMPA) or dimyristoyl phosphatidyl ethanolamine (DMPE) into pure DMPC vesicles reduces the total lasalocid fluorescence relative to that observed in pure DMPC vesicles. Fluorescence lifetime experiments indicate the decrease in fluorescence is not due to reduction of the quantum yield of the bound lasalocid but rather to a reduction in the degree of binding. The sensitivity of total ionophore binding to polar head group composition is similar to that observed for the fluorescent spin probe l-anilino-8-naphthalenesulfonate and indicates... 

Differential Thermal Analysis Studies. Recent studies of pure anhydrous phospholipids (7) using differential thermal analysis (DTA) have revealed the existence of more than one thermal transition when a phospholipid is heated. Thus, 2,3-dimyristoyl-DL-phosphatidylethanolamine shows on heating a marked endothermic transition at about 120°C. and a smaller endothermic transition at about 135°C. (Figure 2). The major thermal transition is not immediately reversible with the phosphatidyl-ethanolamines, and even holding at room temperature for some days does not produce complete reversion to the original form. The transition with the phosphatidylcholines, in contrast, is lower for the same fatty acid residues and is reversible in character. When one of the chains is unsaturated with a cis group, as occurs with a phospholipid such as 3-stearoyl-2-oleoylphosphatidylethanolamine, the main endothermic transition occurs at a lower temperature, about 70°C. The transition temperatures for... 

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