Dimethylbenzyl alcohol

Hemimellitine has been prepared by the action of sodium on 2,3-dimethyliodobenzene and methyl iodide,3 by the reduction of the chloromethylation product of n-xylene,4 and by the catalytic hydrogenolysis of 2,3-dimethylbenzyl alcohol.8 The present procedure is based on the method of Kantor and Hauser.6... 

Hydrolysis of 2,3-dimethylbenzyl acetate (Note 6) by this procedure gave 2,3-dimethylbenzyl alcohol, m.p. 65-66°, in 96% yield. 

Oxidation of cumene to cumene hydroperoxide is usually achieved in three to four oxidizers in series, where the fractional conversion is about the same for each reactor. Fresh cumene and recycled cumene are fed to the first reactor. Air is bubbled in at the bottom of the reactor and leaves at the top of each reactor. The oxidizers are operated at low to moderate pressure. Due to the exothermic nature of the oxidation reaction, heat is generated and must be removed by external cooling. A portion of cumene reacts to form dimethylbenzyl alcohol and acetophenone. Methanol is formed in the acetophenone reaction and is further oxidized to formaldehyde and formic acid. A small amount of water is also formed by the various reactions. The selectivity of the oxidation reaction is a function of oxidation conditions temperature, conversion level, residence time, and oxygen partial pressure. Typical commercial yield of cumene hydroperoxide is about 95 mol % in the oxidizers. The reaction effluent is stripped off unreacted cumene which is then recycled as feedstock. Spent air from the oxidizers is treated to recover 99.99% of the cumene and other volatile organic compounds. 

Photolytic. Major products reported from the photooxidation of isopropylbenzene with nitrogen oxides include nitric acid and lienzaldehyde (Altshuller, 1983). A / -hexane solution containing isopropylbenzene and spread as a thin film (4 mm) on cold water (10 °C) was irradiated by a mercury medium pressure lamp. In 3 h, 22% of the applied isopropylbenzene photooxidized into a,a-dimethylbenzyl alcohol, 2-phenylpropionaldehyde, and allylbenzene (Moza and Feicht, 1989). 

When toluene, benzyl alcohol, and a,a-dimethylbenzyl alcohol are solvated with either water or ammonia and ionized (I - <- S0), a number of reactions... 

Copolymerization of 4-bromo-2,6-dimethylphenol with 2,4,6-trimethylphenol, 4-t-butyl-2,6-dimethylphenol, 2,2-bis(4-hydroxy-3,5-dimethylphenyl)propane, 4-hydroxy-3,5-dimethylbenzyl alcohol and a 4-substituted-2,6-di-r-butylphenol are discussed269. 

Epoxidation, where PO and a,a-dimethylbenzyl alcohol (cumyl alcohol, CA) are obtained from CHP and propene, in the presence of a proprietary heterogeneous epoxidation catalyst. 

Phenol. The manufacture of phenol by the oxidation of benzene is described by Denton (21) and by Simons and McArthur (107). The literature on phenol by the oxidation of cumene is partly covered in the reports of Frank (33), Hawkins (43), and Kharasch (57), mentioned earlier. A brief description and flow sheet of the process is given in Chemical Engineering (16). The patents in this field are mainly held by The Distillers Co., Ltd., Hercules Powder Co., and Allied Chemical and Dye Corp. In this phenol process large amounts of acetone are obtained as a coproduct. It should also be noted that the process may be directed to the production of cumene hydroperoxide and a,a dimethylbenzyl alcohol. Krieble (61) and Kenyon and Boehmer (55) describe the preparation of phenol by the chlorination and sulfonation processes. 

Beilstein Handbook Reference) AI3-05532 Benzenemethanol, a,a-dimethyl- Benzyl alcohol, a,a-dimethyl-BRN 1905012 a-Cumyl alcohol a,a-Dimethylbenzenemethanoi a,a-Dimethylbenzyl alcohol Dimethylphenylcarbinol Dimethylphenylmethanol EINECS 210-539-5 HSDB 5718 1-Hydroxycumene NSC 1261 NSC 212537 Phenyidimethylcarbinol 2-Phenyl-2-propanol. Prisms mp = 36° bp = 202° d ° = 0.9735 Xm B 210, 243, 247, 253, 258, 266, 268 nm (MeOH) insoluble in H2O, soluble in EtOH, Et20, CeHe. AcOH. 

A control transformation with E. coli JM109 (no dioxygenase) cells was also run in parallel with both the NDO and TDO reactions and produced negligible amounts of dimethylphenylsilanol. In another control transformation, cumene, which can be considered the carbon analogue of DMPS, was converted completely into cumyl alcohol (1,1-dimethylbenzyl alcohol) by NDO, while TDO produces exclusively to the c/s-diol Together, these results, support the hypothesis that silanol production was the result of an enzyme-mediated process. 

With dimethylbenzyl alcohol as a polymerization regulator which prevents cross-linking and using animal glue as a suspending agent, a suspension polymer has been prepared. This material gave clear solutions in acetone and could be molded as 85°C and 5000 psi within 10 min. Procedure 8-5 illustrates the polymerization process of this patented process [107]. 

In a 2-liter resin kettle fitted with an addition fiumel, reflux condenser, mechanical stirrer, thermometer, and a means of maintaining an inert atmosphere, to 600 gm of water heated, with stirring, under a nitrogen atmosphere at 80°C, are added 2 gm of animal glue and 35 gm of dimethylbenzyl alcohol. While maintaining a temperature of 80 C, a solution of 15 gm of recrystallized... 

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