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Dilaudid

Hydrogenation of morphine in warm strong acid in the presence of palladium yields dihydromorphinone. Dihydromorphinone was patented by Knoll and Company (D.R.P. 365683) in 1923 and introduced under the trade name of dilaudid (77). One gram of dihydromorphinone hydrochloride dissolves in about 3 ml. of water. [Pg.43]


Dihydromorphinone, Cj,Hjg03N, and derivatives. Dihydromorphinone (LIII MeO HO) is formed when morphine in solution is treated with relatively large quantities of platinum or palladium catalyst under various conditions.It melts at 262-3° and yields an oxime, m.p. > 234°. The hydrochloride is the drug known as dilaudid. On 0-methyla-tion dihydromorphinone yields dihydrocodeinone (see above), and when dissolved in ether and treated with methyllithium the corresponding tertiary alcohol, 6-methyldihydromorphine, CigHggOgN, m.p. 209-211°, Wd ° 14i7° (EtOH), is formed. This on methylation with diazomethane gives 6-methyldihydrocodeine as described above (Small and Rapoport... [Pg.246]

Dilaudid-Atropin(Knoll as USA Dilaudid (Knoll as hydrochloride)-comb. hydrochloride)... [Pg.1028]

Hydromorphone is more soluble than morphine and approximately eight times more active upon parenteral administration. High solubility permits a lower volume of injected fluid, which is important if multiple injections are needed. It begins to work faster than morphine, but lasts for a shorter amount of time. It has a high sedative effect and a lessened capability of causing euphoria. Hydromorphone is used the same way as morphine. Side effects are analogous. Synonyms for this drug are dilaudid and others. [Pg.25]

Powder for injection, lyophilized 250 mg (10 mg/mL after reconstitution) c-ll) DilaudId-HP (Abbott)... [Pg.833]

Hydromorphone (Dilaudid) [C-ll] [Narcotic Analgesic] Uses Pain Action Narcotic analgesic Dose 1-4 mg IV (onset w/in 10 min duration about 3 h) Caution [B (D if prolonged use or high doses near term), ] t resp depression and CNS t effects CNS depressants, phenothiazines, TCA Contra Component sensitivity Disp Tabs 2, 4 mg, 8 mg Liq 5 mg/5 mL or 1 mg/mL inj... [Pg.19]

Hydrocodone Aspirin (Lortab ASA, others) Hydrocodone Ibuprofen (Vicoprofen) Hydromorphone (Dilaudid) Levorphanol... [Pg.54]

Hydrocodone (Hycodan), oxycodone (Roxicodone), dihydrocodeine, hydromorphone (Dilaudid), and oxy-morphone (Numorphan) are derivatives of codeine and morphine. All are indicated for the relief of mild to severe pain or for their antipyretic effects they are often used in combination with nonopioid analgesics. The drugs vary in potency, but their pharmacological effects do not differ significantly from those of codeine or morphine. [Pg.322]

I Brand Name(s) Dilaudid, Dilaudid-5, Dilaudid HP, Hydromorph, Hydrostat IR Chemical Class Opiate derivative phenanthrene derivative... [Pg.597]

Parenteral (generic, Sublimaze) 50 mcg/mL for injection Fentanyl Transdermal System (Duragesic) 12.5, 25, 50, 75, 100 mcg/h delivery Fentanyl Buccal 100, 200, 400, 600, 800 meg oral lozenge Fentanyl Actiq 200, 400, 600, 800, 1200, 1600 meg lozenge on a stick Patient Controlled Transdermal Iontophoretic Fentanyl System 40 meg per dose for delivery Hydromorphone (generic, Dilaudid)... [Pg.706]

Opium alkaloids and derived phenanthrene alkaloids codeine, morphine, (Avinza, Kadian, MSContin, Roxanol), hydromorphone (Dilaudid), oxymorphone (Numorphan), oxycodone (dihydroxycodeinone, a component of Oxycotin, Oxydose, Oxyfast, Percodan, Percocet, Roxicodone, Tylox)... [Pg.1414]

Among the compounds that fall within this class are hydrocodone (e.g., Vicodin), oxycodone (e.g., OxyContin—an oral, controlled-release form of the drug), morphine, fentanyl, codeine, and related medications. Morphine and fentanyl are often used to alleviate severe pain, while codeine is used for milder pain. Other examples of opioids prescribed to relieve pain include propoxyphene (Darvon) hydromorphone (Dilaudid) and meperidine (Demerol), which is used less often because of its side effects. In addition to their effective pain-relieving properties, some of these medications can be used to relieve severe diarrhea (for example, Lomotil, also known as diphenoxylate) or severe coughs (codeine). [Pg.234]


See other pages where Dilaudid is mentioned: [Pg.741]    [Pg.1692]    [Pg.168]    [Pg.1028]    [Pg.187]    [Pg.428]    [Pg.484]    [Pg.495]    [Pg.495]    [Pg.636]    [Pg.111]    [Pg.72]    [Pg.95]    [Pg.30]    [Pg.341]    [Pg.355]    [Pg.833]    [Pg.6]    [Pg.25]    [Pg.186]    [Pg.598]    [Pg.598]    [Pg.598]    [Pg.598]    [Pg.598]    [Pg.75]    [Pg.89]    [Pg.11]    [Pg.194]    [Pg.4]    [Pg.23]   
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Dilaudid (hydromorphone

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