Nuclear magnetic resonance diffusion-ordered spectroscopy

Johnson CS Jr. (1999) Diffusion ordered nuclear magnetic resonance spectroscopy Principles and applications. Progress in NMR Spectroscopy 34 203. 

DOSY NMR 2-dimensional diffusion ordered spectroscopy nuclear magnetic resonance (spectroscopy) dpb bis(dibenzylideneacetone) dppe 1,2-bis(diphenylphosphino)ethane DSC differential scanning calorimetry DV differential viscometry... 

KF Morris, CS Johnson Jr. Diffusion-ordered two-dimensional nuclear magnetic resonance spectroscopy. J Am Chem Soc 114 3139-3141, 1992. 

Solid-state nuclear magnetic resonance (NMR) has been extensively used to assess structural properties, electronic parameters and diffusion behavior of the hydride phases of numerous metals and alloys using mostly transient NMR techniques or low-resolution spectroscopy [3]. The NMR relaxation times are extremely useful to assess various diffusion processes over very wide ranges of hydrogen mobility in crystalline and amorphous phases [3]. In addition, several borohydrides [4-6] and alanates [7-11] have also been characterized by these conventional solid-state NMR methods over the years where most attention was on rotation dynamics of the BHT, A1H4, and AlHe anions detection of order-disorder phase transitions or thermal decomposition. There has been little indication of fast long-range diffusion behavior in any complex hydride studied by NMR to date [4-11]. 

Various new techniques suitable for estimating D are now available fluorescence correlation spectroscopy (FCS) [5], fluorescence recovery after photobleaching (FRAP) [6], pulsed field gradient nuclear magnetic resonance (PFG-NMR) [7], diffusion ordered NMR spectroscopy (DOSY) [8], and others. Among these, FCS and FRAP are popular in biological studies because they are often installed on a commercial LSM system and conveniently coupled with it. 

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