Dicalcium phosphate mechanical properties

The authors determined the mechanical properties of the excipients in this manuscript at or near 0.85 SF except for dicalcium phosphate (DCP). The low SF that could be achieved with DCP ( 0.6) demonstrates that its compressibility was less than the compressibility of the other materials and that relevant comparisons to them could not be easily made. When the SF difference between materials is 0.03 or less, property differences due to SF are normally relatively small and comparisons can be made with confidence, but when the SF difference is greater than 0.03, a meaningful material comparison becomes more difficult to achieve. In that situation, material comparisons using only general qualitative statements are appropriate. The latter scenario was the case with DCP, and this has been discussed in the section Calcium Phosphate Dibasic. In the discussions that follow, excipient mechanical properties were determined at a SF of 0.85 unless otherwise noted. 

Wang M, Yue CY, Chua B (2001) Production and evaluation of hydroxylapatite reinforced polysnUbne for tissue replacement. J Mater Sci Mater in Med 12 821-826 Wang PE, Chaki TK (1993) Sintering behaviour and mechanical properties of hydroxy lapatite and dicalcium phosphate. J Mater Sci Mater in Med 4 150-158 Watanabe S, Nakamura T, Shimizu Y, Hitomi S, Ikada Y (1989) Traumatic sternal segment dislocation in a child. Chest. 96 684-686... 

Second, calcium phosphate nanocoatings possess better biocompatibility and osteoconductive properties than micron-sized coatings. Almost all kinds of calcium phosphates studies by far have exhibited such improvement, including HA, TCP, dicalcium phosphate dehydrate (DCPD or brushite, CaHP0 -2H20), and so on [82,83]. The mechanism(s) behind the significantly enhanced biocompatibility and... 

Injectable bone substitute material consisting of CTS, citric acid, and glucose solution as the liquid phase, and tricalcium phosphate powder as the solid phase, was developed by Liu and coworkers [141]. Four types of cements have been used to investigate the mechanical properties and in vitro biocompatibility of the material. In the presence of citric acid, tricalcium phosphate partially transformed into HAp and dicalcium phosphate. 

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