Dialkyl-dialkylaminoethyl phosphorothioates

Amiton, 0,0-diethyl-S-(2-diethylaminoethyl) phosphorothioate (65) is the sole representative of practical importance of this type of insecticide (Ghosh and Newman. 1955). It has a basic character because of its tertiary nitrogen atom, and forms water-soluble salts with acids. Its oxalic acid salt was introduced under the trade name Tetram.  

According to one method of preparation, 0,0-diethyl phosphorothiochloridate is reacted with the sodium salt of 2-diethylamino-ethanol, and the thiono isomer formed is isomerised by heating  

According to Schrader (1953b), the reaction of sodium diethyl phosphite with 

2-diethylaminoethyl rhodanide gives the required product directly. 

Amiton is a very potent insecticide and acaricide with a strong ovicidal action. 

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