1.1- Dialkoxy-2-nitro

Alkanolate reagieren mit (E)-l-Nitro-l-alkenen in Tetrahydrofuran zu vie. Alkoxy-ni-tro- bzw. Dialkoxy-nitro-Verbindungen2,3 z.B.2 ... 

Purines, N-alkyl-N-phenyl-synthesis, 5, 576 Purines, alkylthio-hydrolysis, 5, 560 Mannich reaction, 5, 536 Michael addition reactions, 5, 536 Purines, S-alkylthio-hydrolysis, 5, 560 Purines, amino-alkylation, 5, 530, 551 IR spectra, 5, 518 reactions, 5, 551-553 with diazonium ions, 5, 538 reduction, 5, 541 UV spectra, 5, 517 Purines, N-amino-synthesis, 5, 595 Purines, aminohydroxy-hydrogenation, 5, 555 reactions, 5, 555 Purines, aminooxo-reactions, 5, 557 thiation, 5, 557 Purines, bromo-synthesis, 5, 557 Purines, chloro-synthesis, 5, 573 Purines, cyano-reactions, 5, 550 Purines, dialkoxy-rearrangement, 5, 558 Purines, diazoreactions, 5, 96 Purines, dioxo-alkylation, 5, 532 Purines, N-glycosyl-, 5, 536 Purines, halo-N-alkylation, 5, 529 hydrogenolysis, 5, 562 reactions, 5, 561-562, 564 with alkoxides, 5, 563 synthesis, 5, 556 Purines, hydrazino-reactions, 5, 553 Purines, hydroxyamino-reactions, 5, 556 Purines, 8-lithiotrimethylsilyl-nucleosides alkylation, 5, 537 Purines, N-methyl-magnetic circular dichroism, 5, 523 Purines, methylthio-bromination, 5, 559 Purines, nitro-reactions, 5, 550, 551 Purines, oxo-alkylation, 5, 532 amination, 5, 557 dipole moments, 5, 522 H NMR, 5, 512 pJfa, 5, 524 reactions, 5, 556-557 with diazonium ions, 5, 538 reduction, 5, 541 thiation, 5, 557 Purines, oxohydro-IR spectra, 5, 518 Purines, selenoxo-synthesis, 5, 597 Purines, thio-acylation, 5, 559 alkylation, 5, 559 Purines, thioxo-acetylation, 5, 559... 

Some reactions of 2,2 -bipyridine /V-oxides have been reported. The l,T-dioxide is nitrated readily to 4,4 -dinitro-2,2 -bipyridine 1,T-dioxide. ° ° °" 2,2 -Bipyridine 1-oxide is also nitrated in the 4 position. The nitro groups in 4,4 -dinitro-2,2 -bipyridine l,T-dioxide are reactive, being replaced by chlorine with concentrated hydrochloric acid," by bromine with acetyl bromide, by hydroxyl with dilute sulfuric acid, and by alkoxy groups with sodium alkoxides. Some of the dialkoxy derivatives are useful catalysts for the oxidation of aromatic compounds. The dinitro dioxide is deoxygenated to 4,4 -dinitro-2,2 -bipyridine with phosphorus trichloride in chloroform, and other substituted l,T-dioxides behave similarly, but with phosphorus trichloride alone, 4,4 -dichloro-2,2 -bipyridine results. The dinitro dioxide is reduced by iron powder in acetic acid to 4,4 -diamino-2,2 -bipyridine, whereas 4,4 -dichloro-2,2 -bipyridine l,T-dioxide is converted to its 4,4 -diamino analogs with amines. Related reactions have been described. ... 

In 1-substituierten Nitro-imidazolen konnen 2-, 4- oder 5-Methyl-Gruppen mit Dialkoxy-dimethylamino-methan (z. B. Dimethoxy-dimethylamino-1074, Dicyclohexyloxy-dimethylami-no-1073, Bis-[dimethylamino]-tert.-butyloxy-methan1143) zu 2-, 4- oder 5-(2-Dimethylamino-ethenyl)-Gruppen umgesetzt werden. Auf diese Weise konnen z. B. 5- (2-Dime thy lamino-ethe-nyl)-l-methyl-4-nitro-101A und 2- (2-Dimethylamino-ethenyl)-1 -methyl-5-nitro-imidazol1013,1143 (weitere Beispiele s.1143) hergestellt werden. 

Die C-Acylierung von Nitro-alkanen mit Trialkoxy-methanen und Zinkchlorid fiihrt zu 1, l-Dialkoxy-2-nitro-alkanen (13-49%) ... 

Generell sind auch (jE )-2-Nitro-1-phenylthio-l-alkene einsetzbar, die unter Abspaltung der Phenylthio-Funktion zu l,1-Dialkoxy-2-nitro-alkanen (77-78%)4reagieren ... 

Preparation of the different nitro derivatives of dialkoxy calix[4]arene crown-6, isolation, and identification of pure isomers of these derivatives should be very useful in subsequent identification of isomers arising from irradiation of calixarenes. For instance, the two isomers of the mononitro derivative (N02 para to alkoxy chain or para to phenoxy) were characterized. From the three possible isomers of the dini-tro derivative, two were isolated and obtained in pure form, thus enabling interpretation of their NMR spectra. The structure of the trinitro derivative was clarified as expected, two nitro moieties are in the para position relative to the two alkoxy chains the third one is para to phenoxy.94... 

Nitro-6-chloropyridazine 1-oxide reacts with nucleophiles with displacement of the 6-chlorine atom (even with acetyl bromide), except with sodium methoxide. Merer, the 3-nitro group is diplaced. Nucleophilic substitution with amines was investigated for various monoalkoxydihalo-or dialkoxyhalopyridazines. Normally, the chlorine atom is replaced, but in 3-chloro-4,6-dialkoxy- or 4-alkoxy-3,6-dichloropyridazines the alkoxy group may be replaced preferentially or concurrently. The 6-chlorine atom of methyl (3,6-dichloropyridazin-4-yl)-acetate was displaced by hydrazine or on hydrolysis. ... 

---