Di-n-butyltin dichloride

Di-/i-butyltin oxide [SI8-08-6] M 248.9, m >300 . It is prepd by hydrolysis of di-n-butyltin dichloride with KOH. Hence wash with a little aq M KOH then H2O and dry at 80 /10mm until the IR is free from OH bands. [Cummings Aust J Chem 18 98 7965.]... 

Ema M, Itami T, Kawaaski H (1991) Teratogenicity of di-n-butyltin dichloride in rats. Toxicology Letters, 58 347-356. 

Farr CH, Reinisch K, Helsen JF, Neubert D (2001) Petential teratogenicity of di-n-butyltin dichloride and ether dibutyltin compounds. Teratogenesis, Carcinogenesis, and Mutagenesis, 21(6) 405-415. 

The nucleophilic displacement of the iodine moiety in 2-iodoben-zoates mediated by triphenyltin hydride and di-n-butyltin dichloride in aqueous solution has been demonstrated (Eq. 6.16).33 For example, 2-iodobenzoic acid reacts with a toluene solution of Ph3SnH/l,3-(N02)2 C6H4/aq. NaHC03 to give 89% yield of salicylic acid. 

Holwerda, D.A. and H.J. Herwig. 1986. Accumulation and metabolic effects of di-n-butyltin dichloride in the freshwater clam, Anodonta anatina. Bull. Environ. Contam. Toxicol. 36 756-762. 

Herwig, H.J. and D.A. Holwerda. 1986. Cytochemical localization of tin in freshwater mussels exposed to di-n-butyltin dichloride. A uaf. Toxicol. 9 117-128. 

Di-/-butylpyrocatechol, 47 Di-f-butylsilyl ditriflate, 189 Di-n-butyltin dichloride, 161 Di-n-butyitin oxide, 501... 

Ketimines.1 Di-n-butyltin dichloride is an efficient catalyst for condensation of cyclic ketones with a primary amine to form an imine. However, ketones with an optically active center at the a-position undergo partial racemization. Extensive loss of optical activity is observed when titanium(IV) chloride is used as catalyst. 

Gaunt IF, Colley J, Grasso P, et al. 1968. Acute and short-term toxicity studies on di-N-butyltin dichloride in rats. Food Cosmet Toxicol 6 599-608. 

Henninghausen G, Merkord J. 1985. Meso-2,3-dimercaptosuccinic acid increases the inhibition of glutathione S-transferase activity from rat liver cytosol supernatants by di-n-butyltin dichloride. Arch Toxicol 57 67-68. 

TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin PCB, polychlorinated biphenyls PBB, polybrominated biphenyls DMBA, 7,12-di-methylbenz[a]anthracene DOTC, di-w-octyltin dichloride DBTC, di-n-butyltin dichloride. 

Second generation products were mixed mono-/di-alkyl tin long-chain mercaptans. The stabilizer is synthesized directly from an appropriate combination of mono-n-butyltin trichloride and di-n-butyltin dichloride, which is reacted with a suitable quantity of /-octyl mercaptoacetate and sodium sulfide. Although the tin content in the stabilizer is increased to about 22%, these products are often used in diluted form to aid in their handling, while reducing losses. 

CCRIS 6321 Chlorid di-n-butylcinicity Di-n-butyl-zinn-dichlorid Di-n-butyltin dichloride Dibutyidichloro-stannane Dibutyidichlorotin Dibu lstannium dichloride Dibutyltin chloride Dibutyltin dichloride Diohlorodibutylstannane Dichlorodibutyltin EINECS 211-670-0 HSDB 6071 NSC 2604 Stannane, dibutyldichloro- Tin, dibutyl-, dichloride. 

Merkord, J., H. Weber, G. Kroning, and G. Henninghausen. 2001. Repeated administration of a mild acute toxic dose of di-n-butyltin dichloride at intervals of 3 weeks induces severe lesions in pancreas and liver of rats. Human and Experimental Toxicology 20 386-392. 

The reaction of di-n-butylbenzo[. The... 

CAS 683-18-1 EINECS/ELINCS 211-670-0 Synonyms DibutyIdichlorostannane Dibutyidichlorotin Di-n-butyidichlorotin Dibutyidichlortin Dibutylstannium dichloride Dibutyltin chloride Di-n-butyltin dichloride Din-butyl tin (IV) dichloride Dichlorodibutylstannane Dichlorodibutyltin Stannane, dibutyidichloro- Tin, dibutyl-, dichloride... 

Di-n-butyltin dichloride Di-n-butyl tin (IV) dichloride. See Dibutyltin dichloride Di-n-butyltin di (dodecanoate). See Dibutyltin dilaurate... 

Because of their widespread use industrially many of the mechanistic studies have involved triaLkyltin chlorides and dialkyltin chlorides. Di-n-butyltin dichloride (DBTC) and tri-n-butyltin chloride (TBTC) are the most widely used organotin compounds because of their relatively low toxicity to humans and their high toxicity to bacteria. We will also look at results from other organisms to indicate possible sites of attack. 

BGI3 distilled into di-n-butoxydi-n-butyltin at -80°, allowed to warm to room temp, whereupon an exothermic reaction occurs, and distilled crude di-n-butyltin dichloride. Y 89%. F. e. s. W. Gerrard and R. G. Rees, Soc. 1964, 3510. 

Five oiganotin compounds used as pesticides or PVC stabilizers (fenbutatin oxide, triphenyltin chloride, tricyclohexyltin hydroxide, di-n-butyltin dichloride and diphenyltin dichloride) were baseline resolved on a cyanopropyl column (A = 430nm, ex 495nm, em) using a 96/2/2 hexane/THF/acetic acid mobile phase [809]. Detection limits of 1-2 ng injected for standards, 20-30 ng/L for surface water, and 200-300 ng/g for soils were obtained when a postcolumn irradiation/morin (3,5,7,2, 4 -pentahydroxyflavone) reaction was used. 

A soln. of di-n-butyltin dichloride in dry ether added dropwise with stirring during 1 hr. to a soln. of 2,2 -dilithiumbiphenyl (prepared in 86-91% yield from 2,2 -dibromobiphenyl and Li-chips in dry ether under Ng), stirring continued 2 hrs. at room temp., then hydrolyzed with HgO-satd. ether 5,5-di-n-butyl-dibenzostannol. Y 64.8%. F. e., also synthesis of non-cyclic stannanes, s. R. Gelius, B. 93, 1759 (1960). 

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