Di-isopropyl ketone

Ketonic hydrolysis to di-isopropyl ketone. Mix 14 g (0.75 mol) of the ester with 30 ml of glacial acetic acid, 10 ml of water and 10 ml of concentrated sulphuric acid, and boil under reflux until evolution of carbon dioxide ceases. Dilute the cooled solution with 180 ml of water, add 100 ml of ether and render alkaline to phenolphthalein with 20 per cent sodium hydroxide solution. Separate the ether layer, extract the aqueous layer with two 50 ml portions of ether, dry the combined ether layer and extracts with anhydrous sodium sulphate, distil off the ether and fractionate the residue. The yield of di-isopropyl ketone (2,4-dimethylpentan-3-one), b.p. 123-124 °C, is 6.5 g (76%). 

FAAS Metals are directly determined by FAAS metals are determined after chelation with ammonium pyrrolidine dithiocarbamate and extraction in methyl isobutyl ketone and metals are determined after chelation with hexamethyleneammonium-hexamethylenedithiocarbamate and extraction in di-isopropyl ketone-xylene Applicable to natural waters 103... 

The supernatant soln. Is cooled In an Ice bath and centrifuged to remove any Hf that ppts. Ta in the supernatant soln. 1b extracted with an equal volume of di-isopropyl ketone which had been previously equilibrated with 6 N HC1-1 N HF. The Ta in the organic phase is back-extracted into an equal volume of H O. 

Attempts to trap other di-alkyl ketyl radicals from methyl-ethyl, di-ethyl, di-n-propyl and di-isopropyl ketones were unsuccessful. The observed spectrum was not that expected from the ketyl radical but in each case it could be identified as that of a radical formed by a hydrogen abstraction from the parent ketone. The structurally similar radicals, CH3—CH—CO—CHg and CH3—CH—CO—CHa—CHg, were formed from methyl-ethyl and di-ethyl ketone respectively and the radical (0113)2—C—CO—CH—(0113)2 was formed by abstraction of the tertiary hydrogen from di-isopropyl ketone. The reaction of di-n-propyl ketone was somewhat unexpected as the spectrum obtained was typical of that for an allyl radical rather than an alkyl radical. It is possible that the allyl radical was formed by abstraction of a hydrogen adjacent to the carboxyl group in a parent molecule followed by an intramolecular rearrangement. Thus... 

Flo. 2.— Distribution coefficients of picrates between water and di-isopropyl ketone... 

A, reservoir for bridge solution B, (Et)4NPi in di-isopropyl ketone C, (Et)4NPi in water D, guard tube. 

Difluoroethane Difluoromethane Di-isopropyl amine Di-isopropyl ether Di-isopropyl ketone... 

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