Dextropropoxyphene Alcohol

In general the opioid analgesics can enhance the CNS depressant effects of alcohol, which has been fatal in some cases this appears to be a particular problem with dextropropoxyphene. Alcohol has been associated with rapid release of hydromorphone and morphine from extended-release preparations, which could result in potentially fatal doses. Acute administration of alcohol and methadone appears to increase the blood levels of methadone. The bioavailability of dextropropoxyphene is increased by alcohol... 

Dextropropoxyphene 9-13 2.5 days Active toxic metabohte which in the elderly and in patients with decreased kidney function may build up (concentrate ) and cause confusion. Risk of pronounced respiratory depression together with alcohol intake. Low risk of abuse... 

Propoxyphene (dextropropoxyphene Darvon) is structurally related to methadone but is much less potent as an analgesic. Compared with codeine, propoxyphene is approximately half as potent and is indicated for the treatment of mild pain. It is not antipyretic or antiinflammatory like aspirin and is less useful than aspirin in most cases of mild pain. Toxicity from propoxyphene, especially in combination with other sedatives, such as alcohol, has led to a decrease in its use. Death following ingestion of alcohol in combination with propoxyphene can occur rapidly (within 20 minutes to 1 hour). The drug is not indicated for those with histories of suicide or depressive illnesses. 

Dextropropoxyphene Dextropropoxyphene, a drug of abuse, and any misuse or overdose of which causes intoxication if taken along with paracetamol or alcohol. The individual develops serious CNS depression leading to death.40-42 Adverse effects can be treated by gastric lavage and administration of activated charcoal and naloxone 43... 

Dexchlorpheniramine, 520 Dexchlorpheniramine maleate, 520 Dexedrine, 519 Dexone, 518 Dexpanthenol, 520 Dextroamphetamine sulphate, 519 Dextroamphetamine, 519 Dextroamphetamine phosphate, 519 Dextrodiphenopyrine, 521 Dextrogesic, 522 Dextromethorphan, 520 Dextromethorphan hydrobromide, 520 Dextromoramide, 521 Dextromoramide acid tartrate, 521 Dextromoramide tartrate, 521 Dextrone X, 853 Dextro-pantothenyl alcohol, 520 Dextropropoxyphene, 29,522 Dextropropoxyphene hydrochloride, 522 Dextropropoxyphene napsylate, 522 Dextrorphan, 521, 523 Dextrostix, 1171 Dexuron, 568, 853 Dexylets, 520, 893 Dezone, 518, 519 DF 118, 544... 

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