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Detection based on electrochemical labels intercalated within dsDNA

3 Detection based on electrochemical labels intercalated within dsDNA [Pg.118]

DNA sensing platforms constructed with Au-NPs (and other NPs) to enhance the DNA immobilization and hybridization performance by increasing the electrode area have also employed for the detection [Pg.118]

Anal) te Modified Electrode Substrate Detection Technique Detection Limit Reference [Pg.119]

Au/SPE gold screen-printed electrode nanoAu-GEC nanogold graphite-epoxy composite. [Pg.119]

In a similar methodology, methylene blue (MB) has recently been used as electrochemical indicator for the preparation of an adenosine triphosphate (ATP) aptasensor [45]. Au-NPs claimed to make more MB interact with DNA on the sensing interface. The DPV peak current corresponding to the MB oxidation decreased with ATP concentration in the 1 x 10 M to 1 x 10 M range, with a detection limit of 0.1 nM. The sensor showed advantages regarding low-cost, rapidity, simple detection, and reusability. [Pg.119]




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