Design fundamentals

2 Basic Design ofEnv me Reactors Under Ideal Conditions. Batch Reactor Continuous Stirred Tank Reactor Under Complete Mixing Continuous Packed-Bed Reactor Under Plug Flow Regime 

A generalized kinetic expression for one-substrate reactions was presented in section 3.3.2 that considers all possible mechanisms for one-substrate reactions (or reactions in which one of the substrates is clearly limiting as it occurs in most hydrolytic reactions in aqueous medium)  

Replacing Eq. 5.2 into Eq. 3.41 and considering inactive ternary enzyme-substrate-inhibitor complexes, the following expression is obtained considering the reaction scheme in section 3.3.2 (Illanes 1994)  

Reactions of synthesis with two substrates can be described according to sequential (ordered or random) or oscillatory (ping-pong) mechanisms, as presented in section 3.4.1 for the reaction of synthesis  

A basic model to describe enzyme reactor operation can be constructed from a material balance of the process and a suitable kinetic expression, as shown in Fig. 3.1. 

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These design fundamentals result in the requirement that space velocity, effective space—time, fraction of bubble gas exchanged with the emulsion gas, bubble residence time, bed expansion relative to settled bed height, and length-to-diameter ratio be held constant. Effective space—time, the product of bubble residence time and fraction of bubble gas exchanged, accounts for the reduction in gas residence time because of the rapid ascent of bubbles, and thereby for the lower conversions compared with a fixed bed with equal gas flow rates and catalyst weights. 

McDuffie, N. G., Bioreactor Design Fundamentals, Butterworth/Heine-mann, Stoneham, Massachusetts, 1991. 

Introduction to Reactor Design Fundamentals for Ideal Systems... 

Introduction to Reactor Design Fundamentals for Ideal Systems 267 Substituting Equation 5-10 into Equation 5-7 gives... 

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