2 -deoxyuridine

Application of this reaction to 2, 2-anhydrouridine (LXXXVII) led to a 3-substituted nucleoside (CIV) which, upon acylation followed by reduction with Raney nickel, yielded 3-deoxyuridine (CV, R = uracilyl). Reductive cleavage of CV, by the sodium-liquid ammonia procedure,72 afforded 3-deoxy-D-en/fAro-pentose ( 3-deoxy-D-ribose ), a result which establishes position 3 as the site originally containing the ethylthio function. The authors suggest,248 as a plausible route to CIV, the initial formation of the anion CII, followed by formation of the 2,3-anhydride structure. The anhydride (CIII) is then attacked, at C3, by the ethanethiol ion, to yield... 

Diazotization of 5-amino-3 -deoxyuridine 231 gave the 5-diazopyrimidooxazocine 232 through a nucleophilic attack of the C-5 oxygen on the electron-deficient C-4 carbon (Scheme 48) <2002W032920>. 

H2O), pKgst 9.3. 3 -Deoxyuridine is recrystallised from Me2CO/MeOH and is dried in a vacuum. [Michelson Todd / Chem Soc 816 7955.]... 

The common structural skeleton of the uridyl peptide antibiotics, the (25,35)-diaminobutyric acid (DABA) residue, serves as a connection point for the 3 -deoxyuridine moiety via a 4, 5 -enamide linkage. The DABA residue is acylated on both nitrogen substituents by peptide chains. 

Deoxy 3 -Deoxy-5-flnoroitridine. 5-Fluoro-3 -deoxyuridine CgHiiFNjOs 246.195 Cryst. (EtOH). Mp 169-171°. 5 -Phosphate [796-66-7]... 

Deoxyuridine, Z-3 2 -Deoxy- j/-uridine, D-354 2 -Deoxyuridine, D-382 3 -Deoxyuridine, D-383 5 -Deoxyuridine, D-384 2 -Deoxyuridine-5 -carboxamide, D-382 2 -Deoxyuridine-5 -carboxylic acid, D-382 2"-Deoxy-5 -uridylic acid, D-382 2 -Deoxy-5-vinyluridine, V-21... 

C-Fluoroadenosine 5 -sulfamate, N-84 2-Fluoroadenosine, F-11 8-Fluoroadenosine, F-12 Fluoroancitabine, F-19 Fluoroblasticidin S, B-39 5-Fluorocytidine, F-13 p-Fluoro-ddA, L-48 2 -Fluoro-2 -deoxyadenosine, D-63 5-Fluoro-3 -deoxycytidine, F-13 5-Fluoro-3 -deoxyuridine, F-18 8-Fluoroerythromycin, E-18 5-C-Fluorogalactosyl fluoride, F-14... 

Process of 3 -fluoro-3 -deoxyuridine (3 -F-3 -dUrd) phosphorolysis was analyzed in the presence of mutPyrNPase 2.5 U of enzyme activity were added to 3 -F-3 -dUrd in 2 mM PPB and the reaction was performed at 80°C with regular monitoring of phosphorolysis degree in the course of 96 h. 

---