Dendrons and dendrimers

Grayson, S., and Frechet, J.M.J. (2001) Convergent dendrons and dendrimers from synthesis to applications. Chem. Rev. 101, 3819-3868. 

Dendrons and dendrimers are the most intensely investigated subset of dendritic polymers. In the past decade over 2000 literature references have appeared on this unique class of structure controlled polymers. The term dendrimer was coined by Tomalia, et al. over 15 years ago in the first reports on poly(amidoamine) (PAMAM) dendrimers [75, 76]. It is derived from the Greek words dendri-(branch tree-like) and meros - part of). Poly(amidoamine) dendrimers constitute the first dendrimer family to be commercialized and undoubtedly represent the most extensively characterized and best understood series at this time. In view of the extensive literature information in this area, much of the remaining overview will focus on PAMAM dendrimers and will... 

ALIPHATIC POLYESTER DENDRONS AND DENDRIMERS BASED ON 2,2-BIS-HYDROXYMETHYLPROPIONIC ACID... 

Al-Jamal KT, Ramaswamy C, Florence AT. Supramolecular stmctures from dendrons and dendrimers. Adv Drug Deliv Rev 2005 57 2238-2270. 

Grayson, S. M., and J. M. J. Frechet. 2001. Convergent dendrons and dendrimers From synthesis to applications. Chemical Reviews 101 3819-67. 

Fig. 11. Branch cell and branch cell assemblies leading to dendrons and dendrimers...

Fig. 18. Various genealogically directed synthesis (GDS) strategies for the construction of dendrons and dendrimers...

Dendrons and dendrimers have been synthesized with a variety of cores, interiors, and surface functionalities. Presently, over twenty different chemical families of dendrons/dendrimers have been reported. 

Fig. 24. Various oligonucleotide branch cell reagents [ A), (B), (C), (D)] suitable for constructing DNA/RNA dendrons and dendrimers...

Convergent Dendrons and Dendrimers from Synthesis to Applications... 

The poly(benzyl ether) dendrimer synthesis is one of only a few convergent syntheses that can produce dendrons and dendrimers in reasonable yields up to the sixth generation. These dendrons, now frequently referred to as Frechet-type dendrons, have been utilized by a number of groups because they are... 

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