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Degranulation polymorphonuclear neutrophils

Meddows-Taylor S, Martin DJ, Tiemessen CT. Impaired interleukin-8-induced degranulation of polymorphonuclear neutrophils from human immunodeficiency virus type 1-infected individuals. Clin Diagn Lab Immunol 1999 6 345-351. [Pg.166]

The majority of tissue reactions are of inflammatory origin. Indeed, most granuloma contain different cell types with inflammatory characteristics, including multinucleated giant cells, histiocytes, plas-mocytes, mast cells, and lymphocytes (Griffith et al. 1987 Nasser et al. 1990). In addition, neutrophilic polymorphonuclear cells frequently exhibit degranulation (Shanbhag etal. 1992). [Pg.376]

PAF stimulates polymorphonuclear leukocytes to aggregate, to release LTs and lysosomal enzymes, and to generate superoxide. PAF also promotes aggregation of monocytes and degranulation of eosinophils. It is chemotactic for eosinophils, neutrophils, and monocytes and promotes endothelial adherence and diapedesis of neutrophils. When given systemically, PAF causes leuko-cytopenia, with neutrophils showing the greatest decline. [Pg.426]


See other pages where Degranulation polymorphonuclear neutrophils is mentioned: [Pg.238]    [Pg.62]    [Pg.434]    [Pg.53]    [Pg.421]    [Pg.807]   


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