Decellularization decellularized extracellular matrix

J.S. Choi, et al., Decellularized extracellular matrix derived from human adipose tissue as a potential scaffold for allograft tissue engineering, J Biomed Mater Res A 97 (2011) 292-299. 

SIS (small intestinal submucosa) Decellularized extracellular matrix Surgery, tissue engineering... 

Others (eg, decellularized extracellular matrix, chitosan, gelatin) Synthetic Polymers (Nonenzymatic Degradation)... 

B.S. Kim, J.S. Choi, J.D. Kim, Y.C. Choi, Y.W. Cho, Recellular-ization of decellularized human adipose-tissue-derived extracellular matrix sheets with other human cell types. Cell Tissue Res. 348 (2012) 559-567. 

M.T. Wolf, K.A. Daly, E.P. Brennan-Pierce, S.A. Johnson, C.A. Carruthers, A. D Amore, S.P. Nagarkar, S.S. Velankar, S.F. Badylak, A hydrogel derived from decellularized dermal extracellular matrix, Biomaterials 33 (29) (2012) 7028-7038. 

Sawkins, M.J., Bowen, W., Dhadda, P, Markides, H., Sidney, L.E., Taylor, A.J., Rose, F.R., Badylak, S.F., Shakesheff, K.M., White, L.J., 2013. Hydrogels derived from demineralized and decellularized bone extracellular matrix. Acta Biomater. 9, 7865-7873. 

Acellular nerve matrix allografts have also been observed as useful biomaterials for nerve regeneration [34]. These allografts preserve extracellular matrix (ECM) components and, therefore, mimic the ECM of peripheral nerves mechanically and physically. In this way, acellular nerve matrices aid in the reconstruction of the peripheral nerve. However, decellularization techniques, such as thermal deceUularization, can damage the ECM structure and fail to extract all cellular components leading to inflammation upon implantation [35]. 

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