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Cytotoxicity bacterial endotoxins

Cytotoxic activated macrophages (CAMs) macrophages that have been treated either in vivo or in vitro by exposme to a combination of bacterial products (such as endotoxin) plus cytokines (particularly interferon-y), rendering them able to kill or damage abnormal cells (cancerous or infected with pathogenic microbe or vims) or pathogen. An important component of the CAMs armamature for this cytotoxic mechanism is production of -NO... [Pg.2984]

In the following, we will focus on in vitro tests for cell compatibility and blood compatibility. In this context, we will also discuss ISO 10993-5 (tests for in vitro cytotoxicity) and ISO 10993-4 (selection of tests for interactions with blood). Finally, the risk of pyrogens in the biomaterial context, especially of bacterial toxins (endotoxins), will be briefly highhghted and selected methods for determining pyrogens/endotoxins (cf. also ISO 10993-11) will be presented. [Pg.175]

See other pages where Cytotoxicity bacterial endotoxins is mentioned: [Pg.220]    [Pg.188]    [Pg.260]    [Pg.525]    [Pg.36]    [Pg.132]    [Pg.699]    [Pg.859]    [Pg.2846]    [Pg.343]   
See also in sourсe #XX -- [ Pg.52 ]



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