Cyclooxygenase-2 selective

Spiegel BMR, Targownik L, Dulai GS, Gralnek IM. The cost-effectiveness of cyclooxygenase-2 selective inhibitors in the management of chronic arthritis. Ann Intern Med 2003 138 795-806. 

Knijff-Dutmer EA et al Platelet function is inhibited by non-selective non-steroidal anti-inflammatory drugs but not by cyclooxygenase-2-selective inhibitors in patients with rheumatoid arthritis. Rheumatology (Oxford) 2002 41 458. [PMID 11961179]... 

Chapter 2. Anti-inflammatory Cyclooxygenase-2 Selective Inhibitors Celecoxib (Celebrex ) and Rofecoxib (Vioxx )... 

Cryer, B., Feldman, M. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs. Am. J. Med. 1998, 104, 413-421. 

Kassahun, K., McIntosh, I. S., Shou, M., Walsh, D. J., Rodeheffer, C., Slaughter, D. E., Geer, L. A., Flalpin, R. A., Agrawal, N., Rodrigues, A. D. Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitor, Drug Metab. Dispos. 

Komhoff, M., Wang, J. L., Cheng, FI. F., Langenbach, R., McKanna, J. A., Flarris, R. C., Breyer, M. D. Cyclooxygenase-2-selective inhibitors impair glomerulogenesis and renal cortical development, Kidney Int. 2000, 57, 414-422. 

Heise G, Grabensee B, Schror K, Heering P (1998) Different actions of the cyclooxygenase 2 selective inhibitor flo-sulide in rats with passive Heymann nephritis. Nephron... 

Breyer MD, Hao C, Qi Z, Breyer MD, Hao C, Qi Z. Cyclooxygenase-2 selective Inhibitors and the kidney. Current Opinion in Critical Care 2001 7 393-400. 

Graham DJ, Campen D, Hui Ret al. Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclooxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs nested case-control study.. Lancet 2005 365 475-481. 

Spilding WM, Reeves MJ, Whelton A. Thromboembolic Cardiovascular Risk Among Arthritis Patients Using Cyclooxygenase-2-Selective Inhibitor or Nonselective Cyclooxygenase Inhibitor Nonsteroidal Anti-inflammatory Drugs. American Journal of... 

Gyllfors P, Bochenek G, Overholt J, et al. Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgesic celecoxib. J Allerg Clin Immunol 2003 111 1116-1121. 

Palomer A, Cabre F, Pascual J, Campos J, Trujillo MA, Entrena A, Gallo MA, Garcia L, Mauleon D, Espinosa A. Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models. J Med Chem 2002 47 1402-1411. 

Puignero V, Queralt J. Effect of topically apphed cyclooxygenase-2-selective inhibitors on arachidonic acid- and tetradecanoylphorbol acetate-induced dermal inflammation in the mouse. Inflammation 1997 21 431-442. 

PunwaniNG. Tramadol pharmacokinetics and itspossible interactions with cyclooxygenase 2-selective nonsteroidal anti-inflammatory drugs. CUn Pharmacol Ther lQOA) 75,363-5. 

The rational basis for the development of cyclooxygenase-2-selective inhibitors was the discovery that there are structural differences between both isoforms in the region of the binding pocket (Fig. 5.87). The end of the hydro-phobic access channel is bordered by a side-pocket, which is in the case of cy-... 

Scheiman JM. Balancing risks and benefits of cyclooxygenase-2 selective nonsteroidal antiinflammatory drugs. Gastroenterol Clin N Am 2009 38 305-314. 

Malan TP Jr, Marsh G, Hakki SI, Grossman E, Traylor L, Hubbard RC. Parecoxib sodium, a parenteral cyclooxygenase 2 selective inhibitor, improves morphine analgesia and is opioid-sparing following total hip arthroplasty. Anesthesiology 2003 98 ... 

Schug S, Joshi G, Camu F, Pan S, Cheung R. Cardiovascular safety of the cyclooxygenase-2 selective inhibitors parecoxib and valdecoxib in the postoperative setting an analysis of integrated data. Anesth Analg 2009 108 299-307. 

Soni P, Shell B, Cawkwell G, Li C, Ma H. The hepatic safety and tolerability of the cyclooxygenase-2 selective NSAID celecoxib pooled analysis of 41 randomized controlled trials. Curr Med Res Opin 2009 25(8) 1841-51. 

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