Methyl-cyclohexanone

A variety of l,2,3,4-tetrahydro-j8-carbolines have been prepared from 3-piperidone phenylhydrazone derivatives. Used initially to obtain pentacyclic derivatives (35) related to the yohimbe alkaloids, this route was later extended to the synthesis of tetracyclic compounds (36). l-Methyl-5,6,7,8-tetrahydro-j8-carboline (37) was prepared in low yield by heating cyclohexanone 2-methyl-3-pyridylhydrazone with zinc chloride, a synthesis probably based on the similar preparation of the tetracyclic compound 38 starting from the corresponding quinolylhydrazine. Abramovitch and Adams extended this approach to the cyclization of cyclohexanone 3-pyri-dylhydrazone (39) itself. The main product was 6,7,8,9-tetrahydro-8-carboline (40), a smaller amount of the j8-isomer (41) also being obtained. This provides a convenient and readily reproducible route to the otherwise difficultly accessible 8-carboline ring system. The favored attack at carbon-2 over carbon-4 of the pyridine nucleus... 

Benzyl-2-methylcyclohexanone Cyclohexanone, 2-benzyl-2-methyl- Cyclohexanone, 2-methyl-2-(phenylmethyl)- (1206-21-9), 76, 244... 

A pressure increase, brought about by an increase in the concentration of the ketone or by the addition of an inert gas, enhances the formation of the unsaturated aldehyde as compared to that of CO. The value of awehyde increases at the expense of 0co> thus, the ketone consumption yield is independent of pressure. This seems to be generally valid in the photolysis of the cyclic ketones it was confirmed, for instance, for cyclopentanone °, cyclohexanone 2-methyl cyclohexanone and 2,6-dimethyl cyclohexanone . An increase in wavelength also favours the formation of the aldehyde as compared to decarbonylation in the photolysis of cyclobutanone , cyclopentanone and cyclohexanone . At 3130 A, the decrease in temperature has a similar effect on the product distribution in the photolysis of cyclopentanone , cyclohexanone , 2-methyl cyclohexanone , and 2,6-dimethyl cyclohexanone to that caused by the increase in wavelength or pressure. However, at shorter wavelengths, the quantum yields seem to be independent of temperature . ... 

Benzyl-6-methylcyclohexanone Cyclohexanone, 2-benzyl-6-methyl-(8) Cyclohexanone, 2-methyl-6-(phenylmethyl)- (9) (24785-76-0) 2-Methylcyclohexanone Cyclohexanone, 2-methyl- (8,9) (583-60-8) Diisopropylamine (8) 2-Propanamine, N-(l-methylethyl)- (9) (108-18-9) Butyllithium Lithium, butyl- (8,9) (109-72-8)... 

---