Cyclohex

The epoxidation method developed by Noyori was subsequently applied to the direct formation of dicarboxylic acids from olefins [55], Cyclohexene was oxidized to adipic acid in 93% yield with the tungstate/ammonium bisulfate system and 4 equivalents of hydrogen peroxide. The selectivity problem associated with the Noyori method was circumvented to a certain degree by the improvements introduced by Jacobs and coworkers [56]. Additional amounts of (aminomethyl)phos-phonic acid and Na2W04 were introduced into the standard catalytic mixture, and the pH of the reaction media was adjusted to 4.2-5 with aqueous NaOH. These changes allowed for the formation of epoxides from ot-pinene, 1 -phenyl- 1-cyclohex-ene, and indene, with high levels of conversion and good selectivity (Scheme 6.3). 

Carba-glycosylamines [2,3,4-trihydroxy-5-(hydroxymethyl)-1 -cyclohex-ylamine] and related compounds are well known to exist as components of the antibiotic validamycin complex and carba-oligosaccharidic alpha amylase inhibitors. ... 

The mixture was stirred for a few minutes at room temperature until two clear phases were produced. To the ice-chilled reaction mixture were successively added osmium tetroxide (4wt% in water, 0.36 mL) and (1-cyclohex -enyl)-acetonitrile (1.73 g). The reaction mixture was stirred vigorously for 8 hours at 0 °C. 

Notes. (1) Cyclohex-1-en-l-ylacetic acid may be prepared from ethyl l -hydroxy-cyclohexylacetate (Expt 5.170) by dehydration to the unsaturated ester followed by acidic hydrolysis to the unsaturated acid. An alternative method from cyclohexanone has been described.191... 

An aromatic Claisen rearrangement has been used as a key step in a total synthesis of racemic heliannuols C and E.18 A formal synthesis of (-)-perhydrohistrionicotoxin has used Claisen rearrangement of an amino acid ester enolate as the key step, in which almost total chirality transfer was observed from (S, )-oct-3-en-2-ol in the sense predicted by a chair-shaped transition state with chelation control of enolate geometry.19 Treatment of 1-(cyclohex-l-enyl)-6-methoxy-2-propargylindanol derivatives with base... 

Rogers, I. H., Manville, J. F., and Sahota, T. (1974). Juvenile hormone analogs in conifers. II. Isolation, identification, and biological activity of c/s-4-[r(R)-5 -dimethyl-3 -oxohexyl]-cyclohexane-1-carboxylicacidand(+)-4(R)-[l (R)-5 -dimethyl-3 -oxohexyl]-1-cyclohex-ene-1-carboxylic acid from Douglas-fir wood. Can. ). Chem. 52, 1192-1199. 

The reactim of 2-cyclohexenone with 2-lithiodithiane occurs in a 1,2-fashion to give the unsaturated hydroxy derivative, which, after rearrangement followed by deprotection, gives 3-hydroxy-1-cyclohex-enecarbaldehyde. ... 

PIFA easily converts succinic acid derivatives (32) to -alanine derivatives (33). Limited use of PIFA (1 equiv.) allows the rearrangement of 3-cyclohexene-1-carboxamide (34) without oxidation of the double bond, as shown in Scheme 12. Cyclohexanone is obtained by the PIFA oxidation of 1-cyclohex-enecarboxamide (35). Selective oxidation of the primary amide (36) occurs without effect on secondary or tertiary amides in the same molecule. The rearrangement of the cyclopropane derivative (37) accompanies the ring cleavage to give the -alanine derivative (38) after treatment with benzyloxycarbonyl chloride. ... 

Valeton), Zingiberaceae Habit. India, China, East Indies. Constit. Yellow coloring matter (curcumin), p.p-dihydroxy -dicinnamoyImethane, p-hyd roxycinnamoyIferu loylmethane, p.a -dimethyibenzyl alcohol, 1 -methyl -4 -acetyl -1 -cyclohex -ene. turmerone. a -phellandrene, sabinene, zingiberene, cine-ol. borneol, caprylic acid, lsoln of curcumin from turmeric Janaki, Bose, J. Indian Chem. Soc. 44, 985 (1967). 

A series of 1-cyclobutenyl nonafliates(nonafluoro-n-butanesulfonates) and 1-cyclohex-enyl triflates has been synthesized from the corresponding ketones and their solvolyses were also investigated78-80. 

Figure 11 Cloud-point temperature of micellar solutions as a function of the ethylene oxide chain length the hydrophobic part is an alkyl chain with 8 ( ), 10 ( ), 12 ( ), or 16 ( ) carbon atoms. Data from Ref. 51. The sjunbols ( ) represent the phase-inversion temperature for a 1 1 cyclohex-ane-water emulsion containing 5% of commercial ethylene oxide based emulsifiers having dodecylalkyl chains as a hydrophobic group. (Data from Ref. 54.)...

CAS 6837-24-7 EINECS/ELINCS 229-919-7 Synonyms 1-Cyclohexyl-2-pyrrolidinone N-Cyclohexylpyrrolidinone 1-Cyclohexyl-2-pyrrolidone 2-Pyrrolidinone, 1-cyclohex -... 

Synonyms p-Cetone p-Cyclocitrylidenebutanone p-lonone, methyl- P-lraldeine 1-Methyl-P-ionone P-Methylionone 1-Penten-3-one, 1-(2,6,6-trimethyl-1 -cyclohexen-1 -yl)- 5-(2,6,6-Trimethyl-1 -cyclohexen-1 -yl)-4-penten-3-one 5-(2,6,6-Trimethyl-1-cyclohexenyl)-4-penten-3-one 1 -(2,6,6-T rimethyl-1 -cyclohex-1 -yl)-1 -penten-3-one Empincai C14H22O... 

S) -3,7-Dimethylocta-1,6-dien-3-ol (1R,2S,5R)-5-Methyl-2-propan-2-ylcyclohexan-1-ol (lR-exo)-1,2,7,7-Tetramethylbicyclo(2.2.1]heptan-2-ol (lS,2S,5R)-5-Methyl-2-propan-2-ylcyclohexan-1-ol (Z)-3,7-Dimethylocta-2,6-dien-1-ol [(S)-4-Prop-1-en-2-ylcyclohex-1-en-1-yl]methanol (lp,2p,5a)-4-Methyl-l-propan-2-ylbicyclo(3.1.0]hexan-4-ol (S)-4-Methyl-1-propan-2-ylcyclohex-3-en-1-ol (/ )-2-(4-Methyl-1-cyclohex-3-en-1-yl)propan-2-ol... 

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