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Carba-glycosylamines

Carba-glycosylamines [2,3,4-trihydroxy-5-(hydroxymethyl)-1 -cyclohex-ylamine] and related compounds are well known to exist as components of the antibiotic validamycin complex and carba-oligosaccharidic alpha amylase inhibitors. ... [Pg.52]

Microbial degradation of validamycin A (8) with a cell suspension of Pseudomonas dentrificans afforded validamine (202) and valienamine (203). Hydrogenolysis of validamycin B, followed by acid hydrolysis, yielded hydroxy validamine (204). Valiolamine (205) was isolated and shown to be a component of validamycin G. ° Biosynthesis of these carba-glycosylamines was extensively studied, and the intramolecular aldol addition of the... [Pg.52]

Inhibitory Activity of Some Carba-glycosylamines against Three Enzymes... [Pg.89]

See other pages where Carba-glycosylamines is mentioned: [Pg.21]    [Pg.21]    [Pg.52]    [Pg.64]    [Pg.88]    [Pg.21]    [Pg.21]    [Pg.52]    [Pg.64]    [Pg.88]    [Pg.367]    [Pg.351]   


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Carba

Glycosylamines

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