Current Progress

C. L. Hussey, in Chemistry of Nonaque-ous Solutions - Current Progress (G. Mamantov, A. I. Popov eds.),... 

As an example of the fascinating current progress, Dr. Spencer will describe a beautiful piece of research on the isolation and structure proof of the toxin from Helminthosporium sativum, an important... 

Steinkiihler C, Koch U, Narjes F et al (2001) Hepatitis C vims serine protease inhibitors current progress and future challenges. CurrMedChem 8 919-932... 

Puls RL, Emery S (2006) Therapeutic vaccination against HIV current progress and future possibilities, Clin Sci (Lond) 110 59-71... 

Current progress in the synthesis and properties of pyrrolylphosphazenes is summarized. The differences in reactivity of the cyclic trimer (NPC12)3, and high polymer (NPC12)X, toward the pyrrolide nucleophile are discussed. Efforts to induce electronic conductivity in the polyphosphazenes are reviewed with particular emphasis on polybis (pyrrolyl) phosphazene. 

Apart from the ability of PBPP to undergo electroxidation, this polymer is significantly different from previously reported polyphosphazenes, both in preparation and in properties. Although a complete picture of the chemistry of this polymer has yet to emerge, our current progress will be reviewed in the present article. 

Therefore any attempt to model the spatial occurrence and fate of chemicals in the environment will require an appropriate choice of all the factors discussed above, which have a definite influence on the behavior of the chemicals considered. Figure 2 summarizes some of the most relevant. It is worth mentioning that the availability of spatial data sets has been greatly enhanced by the current progress achieved on remote sensing technologies [57, 58]. 

Shurki, A. Warshel, A., Structure/function correlations of proteins using MM, QM/MM and related approaches methods, concepts, pitfalls, and current progress, Adv. Prot. Chem. 2003, 66, 249-313... 

Metal-sulfur aggregates are now known to occur in biological systems as the active sites of a significant number of metalloenzymes, and clarification of their detailed structures are currently progressing rapidly. In consideration of the results of these studies, many researchers are attempting to synthesize the direct structural models as well as the functional models of the active sites of natural enzymes that promote various important reactions in the biological systems under ambient conditions, which presumably leads in the near future to the... 

Secchi, A., Di Carlo, V., and Pozza, G. 1997. Pancreas and islet transplantation - current progress, problems and perspectives. Hormone and Metabolic Research 29(1), 1-8. 

Singh, M. and O Hagan, D. 2002. Recent advances in vaccine adjuvants. Pharmaceutical Research 19(6), 715-728. Spearman, P. 2006. Current progress in the development of HIV vaccines. Current Pharmaceutical Design 12(9), 1147-1167. 

Barnes, S. and Prasain, J., Current progress in the use of traditional medicines and nutraceuticals, Curr Opin Plant Biol, 8, 324, 2005. 

Which model provides the best representation for local mobility in a particular group remains unclear, as a detailed picture of protein dynamics is yet to be painted. This information is not directly available from NMR measurements that are necessarily limited by the number of experimentally available parameters. Additional knowledge is required in order to translate these experimental data into a reliable motional picture of a protein. At this stage, molecular dynamic simulations could prove extremely valuable, because they can provide complete characterization of atomic motions for all atoms in a molecule and at all instants of the simulated trajectory. This direction becomes particularly promising with the current progress in computational resources, when the length of a simulated trajectory approaches the NMR-relevant time scales [23, 63, 64]. 

When the potential content of this issue was initially discussed with the authors from industry and academia it was immediately clear that the various chapters should give a general overview, but should focus on developments of the last decade. After having finished the project we can state that this goal has been achieved. Thus, the reader will find a balanced view of basic knowledge and current progress. 

N. Karousis, N. Tagmatarchis, Current progress on the chemical modification of carbon nanotubes, Chemical Reviews, vol. 110, pp. 5366-5397, 2010. 

---