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Curare-like effects

Neuromuscular blockade Neurotoxicity can occur. Aminoglycosides may aggravate muscle weakness because of a potential curare-like effect on the neuromuscular junction. [Pg.1646]

In very high doses, aminoglycosides can produce a curare-like effect with neuromuscular blockade that results in respiratory paralysis. This paralysis is usually reversible by calcium gluconate (given promptly) or neostigmine. Hypersensitivity occurs infrequently. [Pg.1023]

With magnesium infusion therapy, therapeutic ranges of 1.1 to 2.5 mmol L are achieved in serum. Decreased neuromuscular transmission is observed at 2.5 to 3.5 mmol L , while higher serum magnesium concentrations lead to curare-like effects which can be overcome by calcium infusion. Cardiac arrest occurs at serum concentrations of 10 to 12.5 mmol L. ... [Pg.595]

Craig LE (1955) Curare-like Effects. In Manske RHF (ed) The Alkaloids Chemistry and Physiology. Vol. 5 - Pharmacology. Academic Press, New York, p 265 ff... [Pg.62]

How far the acetylcholine-like activity of thiamine, postulated by Kalz (1942), can be used to explain the observed anaphylactoid phenomena has not been discussed in the literature. The same applies to its curare-like effects, as reported by Barazzone and Lambelet (1954), as well as to its effects on nervous tissue (Cooper and PiNCUS 1979). Neither does the literature consider the role thiaminases... [Pg.670]

Complete saponification of aconitine produces an alkan-olamine, aconine (36), that lacks the cardiac effects of aconitine but has antiarrhythmic properties. The compound has curare-like effects on neuromuscular transmission, often resulting in death from respiratory paralysis (Benn and Jacyno, 1983). [Pg.675]


See other pages where Curare-like effects is mentioned: [Pg.748]    [Pg.242]    [Pg.125]    [Pg.413]    [Pg.217]    [Pg.771]    [Pg.326]    [Pg.378]    [Pg.312]    [Pg.125]    [Pg.9]    [Pg.291]    [Pg.355]    [Pg.771]    [Pg.326]    [Pg.262]    [Pg.427]    [Pg.379]    [Pg.172]    [Pg.265]    [Pg.275]    [Pg.399]    [Pg.119]    [Pg.593]    [Pg.6916]    [Pg.391]    [Pg.343]    [Pg.539]    [Pg.314]    [Pg.341]    [Pg.414]   
See also in sourсe #XX -- [ Pg.5 , Pg.259 ]

See also in sourсe #XX -- [ Pg.5 , Pg.259 ]

See also in sourсe #XX -- [ Pg.265 ]

See also in sourсe #XX -- [ Pg.675 ]




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Curare

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