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Crystals drug substance, process chemistry

The example of the polymorphs (allotropes) of carbon illustrate the key messages of this chapter different crystal forms of a substance can possess very different properties and behave as different materials. This concept has important implications in all fields of chemistry associated with the production and commercialization of molecules in the form of crystalline materials (drugs, pigments, agrochemicals and food additives, explosives, etc). The producer, in fact, needs to know not only the exact nature of the material in the production and marketing process, but also its stability with time, the variability of its chemical and physical properties as a function of the crystal form, etc. In some areas, e.g. the pharmaceutical industry, the search for and characterization of crystal forms of the API has become a crucial step for the choice of the best form for formulation, production, stability and for intellectual property protection. [Pg.295]


See other pages where Crystals drug substance, process chemistry is mentioned: [Pg.202]    [Pg.90]    [Pg.58]    [Pg.302]    [Pg.202]    [Pg.137]    [Pg.47]    [Pg.4]    [Pg.12]   
See also in sourсe #XX -- [ Pg.247 , Pg.248 , Pg.249 ]




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Drug processing

Drug substance crystallization

Drug substances

Process chemistry

Substances processed

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