Crystallin structural surface template

The location of the domain-binding site was determined by multiple sequence alignment, estimation of the sequence pattern variability, and properties of residues for particular portions of tiie structural surface template. The template prepared for the bovine yB- and pB2-crystallins was described above (Fig. 1). The sequences of mouse PA3- and PB2-aystallins were aligned with bovine yB-and PB2-crystallins, and corresponding residues were placed within the structural template. The sequence variability score was calculated for each residue in the surface template as described in the caption to Fig. 2. The location of the common domain-binding site for the bovine yB- and PB2-ciystallins and mouse PA3- and PB2-ciystallins, was determined by considering the residue positions with a positive sequence variability score (> 0) and the residues with consoved properties in corresponding portions of yB- and PB2-crystallins. 

In addition to the opportunities for new materials synthesis and characterization along these lines, transport properties, rheology, and processing techniques for liquid crystal polymers are essentially unexplored. Experiences with synthesis of polymer structure based on these liquid crystal templates may open up other creative avenues for template synthesis, for example, inside other crystalline structures, chlathrates, or zeolites, or on surfaces [4], Composites, alloys, or mixtures of liquid crystalline and flexible polymers may produce new materials. 

The use of ordered supramolecular assemblies, such as micelles, monolayers, vesicles, inverted micelles, and lyotropic liquid crystalline systems, allows for the controlled nucleation of inorganic materials on molecular templates with well-defined structure and surface chemistry. Poly(propyleneimine) dendrimers modified with long aliphatic chains are a new class of amphiphiles which display a variety of aggregation states due to their conformational flexibility [38]. In the presence of octadecylamine, poly(propyleneimine) dendrimers modified with long alkyl chains self-assemble to form remarkably rigid and well-defined aggregates. When the aggregate dispersion was injected into a supersaturated... 

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