Cross-activation

Manager narrative—Summary of all of the activities, relations with other agencies and community groups, relations with other Red Cross activities, significant or unusual factors in the operation, recommendations for future study or actions... 

However, in other situations, there will be a strong sensitivity to details in the interatomic potential. This is the case when the physics and chemistry is governed by rare events, like crossing activation barriers and the breaking and forming of chemical bonds. If the transition state is not well-characterized and included carefully in the parameterization data base for the model potential, the activation barrier is very likely to be described erroneously by the model potential, leading to wrong transition rates. This is where ab initio methods are needed. 

The net physiological consequences of immune-mediated myelin disruption are partial or total conduction block, slowing of conduction, and ephaptic cross-activation due to disruption of salutatory conduction mediated by the nodes of... 

There are no reports of cross-activity of murine IL-14. Chromosomal Location... 

Noeske,T., Sasse, B.C., Stark, H., Parsons, C.G., Weil, T. and Schneider, G. (2006) Predicting compound selectivity by self-organizing maps cross-activities of metabotropic glutamate receptor antagonists. ChemMedChem, 1, 1066-1068. 

Autoxidation mechanism, Cross-activation, Nitric radicals. Reactors, Sulphoxy radicals Introduction... 

The widely held view that reactions of relatively low rate constants may be safely neglected in the modelling of aqueous phase chemistry should be verified. As shown for the cross-activation of S(IV) and nitrate, the neglected reactions may accelerate, possibly by orders of magnitude, due to an increase of the concentration of inorganic components in desiccating aerosols. 

Because cAMP is a known inhibitor of VSMC proliferation in vitro (Fukumoto etal., 1988 Jonzon etal., 1985 Loesberg etal., 1985 Morisaki et al., 1988 Nakaki et al., 1990b Souness et al., 1992), we were interested to determine whether the inhibition of cell proliferation by cGMP was due to the activation of PKA instead of PKG. Such cross-activation of PKA... 

Jiang, H., Colbran, J. L., Francis, S. H., et al. (1992). Direct evidence for cross-activation of cGMP-dependent protein kinase by cAMP in pig coronary arteries. J. Biol. Chem. 267, 1015-1019. 

From an experimental point of view, it is of interest to note that both situations appear to be encountered, depending on the cell type. Thus, while the first Ca spike has often the same magnitude as the successive ones and occurs after a finite latency in hepatocytes (see Rooney et ai, 1989, and also Fig. 3 in Woods et al., 1987), as predicted by the two-pool model, the first spike is larger and occurs immediately upon stimulation in fibroblasts (Harootunian et ai, 1988, 1991), in accordance with the predictions of the one-pool model based on CICR. In the latter cells, however, experimental observations (Harootunian et al, 1991) can also be accounted for in terms of a mechanism involving the cross-activation of Ca and IP3 (Meyer Stryer, 1988). 

The system (1.16) is said to be of the cross activator-inhibitor type if the Jacobian has the structure... 

The Brusselator is a cross activator-inhibitor system if b > 1. The trace T and determinant A of the Jacobian are given by... 

The Schnakenberg model is a cross activator-inhibitor system iib > a. The deter-minant of the Jacobian is also always positive, h. = a + b), and no stationary bifurcation can occur. The Hopf threshold b is given by the cubic equation... 

Rojas A, Liu G, Coleman I, Nelson PS, Zhang M, Dash R, Fisher PB, Plymate SR, Wu JD. IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR. Oncogene. 2011 30 2345-55. 

In order to observe the stereoselective behavior of the surface, the kink site and a chiral center of the enantiomeric molecule have to be involved in the adsorption process that yields the reaction products. Moreover, owing to the symmetry rules, crossed activity has to be observed, that is, the behavior of an / surface with an S... 

Joseph JA, Kowatch MA, Maki T, Roth GS. Selective cross activation/inhihition of second messenger systems and the reduction of age-related deficits in the muscarinic control of dopamine release from perfused rat striata. Brain Res 1990 ... 

---