Coupling of halides

Dialkyl arylphosphonates and alkenylphosphonates are prepared by the coupling of halides or triflates with the dialkyl phosphonate 783[64l-643]. 

The original synthetic processes using organonickel compounds involved the coupling of halides. Allylic halides react with nickel carbonyl, Ni(CO)4, to give re-ally I... 

Hydrogenolysis of benzyl alcohols 0-79 Reduction of benzylic ethers 0-86 Coupling of halides containing aryl groups... 

Treatment of epoxides with SOCI2, Ph3P and CCI4 or Ph3PCI2 0-76 Reduction of trihalides 0-87 Coupling of halides with trihalides... 

The cyclization of a-chloroacetanilides reported by Buchwald may also involve C-H activation (also Scheme 5). As mentioned above, acetanilides are among the most reactive substrates in this reaction. The presence of a base (Et3N), and 2-PhC6H4PBu2 as the ligand, are conditions more typical of cross-coupling of halides and therefore the sequence may start this way, followed by intramolecular... 

Cross-Coupling of Halides. 4,4-Dimethyl-1-phenylpenta-1,2-diene has been prepared using a ((-)-(2f ,3f )-DIOP)PdCl2-catalyzed cross-coupling reaction, although low enantioselectivity was observed (eq 5). ... 

Coupling reactions. In the presence of indium, Wurtz coupling of halides and pinacol coupling of aromatic aldehydes," the latter with assistance of ultrasound, have been reported. 

IT/ coupling of halides and pinacol d ultrasound, have been reported, fs Ksth meso and dl isomers) cl to afford ( )-alkenes. 

To conclude, we have demonstrated a proof-of-principle reaction of the covalent coupling of halide-substituted benzoic acid molecules on a bulk insulator, namely calcite(10.4). Depending on the number and position of the halide substitution, we can rationally design the structure of the resulting conjugated oligomers. 

Oacylation in peptide synthesis 18,435 suppl. 26 Oacyl group migration 13,255 suppl. 26 allyl rearrangement 27, 578 coupling of halides 11, 731 suppl. 27 epimerization during oxidation 16, 319 suppl. 26 oxidation, allylic 19, 307 suppl. 28... 

Further examples of the coupling of halides are included in section 70 (Alkyls and Aryls from Halides and Sulfonates)... 

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