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Catalyzed Coupling of Amides with Aryl Halides

Copper-Catalyzed Coupling of Amides with Aryl Halides [Pg.925]

The use of ligated copper catalysts has dramatically improved the coupling of aryl halides with amides—the Goldberg reaction. . This reaction has been studied intensively because of the utility of the products and the limitations in scope and efficiency of the palladium-catalyzed coupling of aryl halides with amides. Moreover, it is the process that occurs with the broadest scope when conducted with certain ancillary ligands. [Pg.925]


Scheme 11 Copper(I) oxide/(Ll or L2) or copper iodide/L25-catalyzed coupling of amides with aryl halides... Scheme 11 Copper(I) oxide/(Ll or L2) or copper iodide/L25-catalyzed coupling of amides with aryl halides...



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Amidation aryl halides

Amide arylation coupling

Amide halides

Amides arylation

Amides coupling

Aryl amides

Aryl coupling

Arylation of Amides

Arylation of aryl halides

Coupling of aryl halides

Coupling of halides

Coupling with aryl halides

Halides, aryl coupling

Halides, aryl, arylation catalyzed

Halides, aryl, arylation coupling

With aryl halides

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