Cough prevalence

Sebastian JL, McKinney WP, Kaufman J, et al. Angiotensin-converting enzyme inhibitors and cough Prevalence in an outpatient medical chnic population. Chest 1991 99 36-39. 

Lundback B, Nystrom L, Rosenhall L, Stjemberg N (1991) Obstructive lung disease in northern Sweden respiratory symptoms assessed in a postal survey, Eur Respir J 4 257-266 McGarvey LP, Ing AJ (2004) Idiopathic cough, prevalence and underlying mechanisms, Pulm... 

A syndrome known as mill fever, which may or may not be related to the development of byssinosis, has been described in some persons unaccustomed to breathing cotton dust. Shortly after exposure, there is development of malaise, cough, fever, chills, and upper respiratory symptoms these may recur daily for days to months until acclimatization takes place and symptoms disappear. TTlerance may be lost temporarily after a period of absence from exposure, or if exposure to a greater concentration of dust occurs. The exact prevalence of mill fever among new employees is unknown, but estimates range from 10% to 80%. ... 

In a study of 80 talc workers, there was an excess prevalence of productive cough and of criteria of chronic obstructive lung dis-... 

Ipratropium is virtually devoid of the CNS side effects associated with atropine. The most prevalent peripheral side effects are dry mouth, headache, nervousness, dizziness, nausea, and cough. Unlike atropine, ipratropium does not inhibit mucociliary clearance and thus does not promote the accumulation of secretions in the lower airways. 

Most of the toxic effects of vanadium compounds result from local irritation of the eyes and upper respiratory tract rather than systemic toxicity. The only clearly documented effect of exposure to vanadium dust is upper respiratory tract irritation characterized by rhinitis, wheezing, nasal hemorrhage, conjunctivitis, cough, sore throat, and chest pain. Case studies have described die onset of asthma after heavy exposure to vanadium compounds, blit clinical studies to date have not detected an increased prevalence of asthma in workers exposed to vanadium. 

Adverse effects Pulmonary toxicity is the most serious adverse effect, progressing from rales, cough, and infiltrate to potentially fatal fibrosis. Mucocutaneous reactions and alopecia are common. Hypertrophic skin changes and hyperpigmentation of the hands are prevalent. There is a high incidence of fever and chills and a low incidence of serious anaphylactoid reactions. Bleomycin is unusual in that myelosuppression is rare. 

Asthma an allergic or autoimmune lung Inflammatory condition, the principal symptoms of which are cough, chest tightness and wheeze. It affects about 5% of the population at some time in their life. Prevalence has Increased in recent years, especially in children. 

Dose and end point used for MRL derivation 12.5 ppm for sense of smell, prevalence of respiratory symptoms (cough, bronchitis, wheeze, dyspnea, and others), eye and throat irritation, and lung function parameters (FVC, FEVi, FEV/FVC, FEF50, and FEF75) in humans exposed for an average of 15 years in a soda ash plant. 

Chronic cough is not uncommon and its prevalence varies from 9 to 33% of the population, and there is an association with cigarette smoking (Cullinan 1992 Ford et al. 2006 Zemp et al. 1999), in that chronic smokers have a threefold increase in prevalence of chronic cough compared with never smokers and ex-smokers (Zemp et al. 1999). Other associations are reported too with asthma or respiratory... 

Culhnan P (1992) Persistent cough and sputum Prevalence and clinical characteristics in south east England, Respir Med 86 143-149... 

Chronic cough which persists for more than 3 weeks is also a common symptom in me general population and its prevalence in the USA and Europe is around... 

Chung KF, Pavord ID (2008) Prevalence, pathogenesis and causes of chronic cough. Lancet 371 1364-74... 

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