Cinchonae cortex

Chloroform-dielhylainine (90 10) Chinae cortex Cinchona alkaloids... 

Quinine (44), cinchonicinol (45), and cinchonaminone (46), isolated from Cincho-nae cortex Cinchona succiruba, Rubiaceae), inhibited MAO from bovine plasma in assays using benzylamine as the substrate [68], The IC50 values calculated for MAO inhibition were 16 pM (44), 12 pM (45), and 32 pM (46), and kinetic experiments indicated that quinine (44) acted as a competitive MAO inhibitor. 

Peruvian bark. 1. Cinchona pallida. Pale bark. 2. Cinchona rubra. Red bark. 3. Cinchona flava. Yellow bark. Cinchona lancifolia. Lond. 10. Cortex. The bark. Cinchona oblongifolia. Lond. 10. Cortex. The bark. Cinchona cordifolia. Lond. 10. Cortex. The bark. 

CINCHONA BARK, cinchona cortex is described under section POI B. 

Test mixtures Cinchona alkaloids test mixture for Cinchonae (Chinae) cortex (DAB 10)... 

Chinae cortex Ciuchonae cortex Red Cinchona bark Cinchona pubescens VAHL (syn. C. sucdrubra PAVON) DAB 10, OAB, Helv. VII, MD DAC 86 (tinct.)... 

Fig. I2A In the R, range 0.05-0.25 both Cinchona (Chinae Cortex) extracts show six light blue fluorescent alkaloid zones in UV-365 nm. They can be differentiated on the basis of their quinine (Tl) content. In C. calisaya cortex (1) quinine counts as a major alkaloid. C.

Cerevisiffi Fermentum. Cinchona Flavse Cortex. Capri Sulphas. 

Cmchona alkaloids. Indole alkaloids (cinchonamine group) and quinoline alkaloids (cinchonine group), only the latter group is of therapeutic significance. C. a. are isolated from Cinchona bark (Jesuit s bark Cin-chonae cortex). The name is derived from the Indian word quina (bark). The drug consists of the dried tube... 

Common/vernacular names Red bark, red Peruvian bark, cinchona rubra (C. pubescens), yellow bark, calisaya bark, ledger bark, brown bark, cinchona flava (C. calisaya and C. ledgeriana), Jesuit s bark, Peruvian bark, China bark, cortex chinae, and fever tree. 

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