Controlled release of active agents

Carrier materials and degradable matrices can be produced from PHAs and are desired in many fields, such as agriculture, food technology, or pharmacy. Compounds that can be released from these matrices at controlled rates include drugs, hormones, pesticides, antibiotics, dyestuffs, or fiavours [111]. 

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Price, R. and Gaber, B. Controlled Release of Active Agents Using Inorganic Tubules, US Patent 5,651,976. Price, R. Sustained Delivery of Active Compounds from Tubules with Rational Control, US Patent 5,705,191. Price, R. Method of Controlled Release and Controlled Release Microstructures, US Patent 6,280,759. Price, R. Efficient Method for Subsurface Treatment, Including Squeeze Treatment, US Patent6, 401,816. 

Gaber,B.,Price,R.,Santos,J.P.andVittal, V. (2001) Entrapment and controlled release of active agents from halloysite. Rocks Minerals, 76, 211-215. 

Heller J. Use of pol3nners in controlled release of active agents. In Robinson JR, Lee VHL, eds. Controlled Drug Delivery. New York Marcel Dekker, 1987 179-212. 

Andersen, C. and Pedersen, M., Chewing gum composition with accelerated, controlled release of active agents. U.S. Patent 5487902. 

Heller, J., 1987. Use of polymers in controlled release of active agents in controlled drug delivery. In Robinson, J.R., Lee, V.H.L. (Eds.), Fundamentals and Apphcations, second ed. Marcel Dekker, New York, pp. 210—280. 

Controlled release of active agents from microcapsules embedded in textile structures... 

A design of textile structures intended for controlled release of active agents could be categorized depending on the incorporation of the active agent into the substrate. Possible approaches are schematically shown in Fig. 5.3. 

The large surface area of microcapsules allows for the formation of a uniform and continuous coating on the surface of the fabric as well as in between the fibers (Liu et al., 2013). The reasons for microcapsules playing an important role in the controlled release of active agents could be found in the uniformity and reproducibility in release (Singh et al., 2010). The following sections will focus on microcapsule formation and their embedding into textile stmctures. 

However, functions of these smart textile stmctures could still be improved and their role optimized. Bringing the textile/microcapsule systems for controlled release of active agents to a higher level demands a multidisciplinary approach. Considering all aspects of the controlled release systems such as active agent formulations, microcapsule polymer wall composition, encapsulation approach, and embedding loaded microcapsules into textile structures could push the limits of smart textiles even further. 

Price, R. Gaber, B. Controled release of active agents using inorganic tubules. Pp.,5651976, US Patent. 

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