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Hydrogels controlled release drug delivery systems

The eoneept of mueoadhesion in drug delivery was introduced in the field of controlled-release drug delivery systems in the early 1980s [2,3]. Thereafter, several researchers have focused on the investigations of the interfacial phenomena of mucoadhesive hydrogels (and of other type mucoadhesive compounds) with the mucus. Several techniques of studying these interactions were evaluated both in vitro and... [Pg.169]

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