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Contaminants, dietary, effect

Clinical manifestation of vitamin B 2 deficiency is usually a result of absence of the gastric absorptive (intrinsic) factor. Dietary deficiency of vitamin B 2 is uncommon and may take 20 to 30 years to develop, even in healthy adults who foUow a strict vegetarian regimen. An effective enterohepatic recycling of the vitamin plus small amounts from bacterial sources and other contaminants greatly minimizes the risk of a complete dietary deficiency. Individuals who have a defect in vitamin B 2 absorption, however, may develop a deficiency within three to seven years. [Pg.112]

The application of flavonoids for the treatment of various diseases associated with free radical overproduction is considered in Chapter 29. However, it seems useful to discuss here some studies describing the activity of flavonoids under certain pathophysiological conditions. Oral pretreatment with rutin of rats, in which gastric lesions were induced by the administration of 100% ethanol, resulted in the reduction of the area of gastric lesions [157]. Rutin was found to be an effective inhibitor of TBAR products in the gastric mucosa induced by 50%i ethanol [158]. Rutin and quercetin were active in the reduction of azoxymethanol-induced colonic neoplasma and focal area of dysplasia in the mice [159], Chemopreventive effects of quercetin and rutin were also shown in normal and azoxymethane-treated mouse colon [160]. Flavonoids exhibited radioprotective effect on 7-ray irradiated mice [161], which was correlated with their antioxidative activity. Dietary flavones and flavonols protected against the toxicity of the environmental contaminant dioxin [162], Rutin inhibited ovariectomy-induced osteopenia in rats [163],... [Pg.867]

Lowe, T.P., T.W. May, W.G. Brumbaugh, and D.A. Kane. 1985. National Contaminant Biomonitoring Program concentrations of seven elements in freshwater fish, 1978-1981. Arch. Environ. Contam. Toxicol. 14 363-388. Lu, J. and G.F. Combs, Jr. 1988a. Effects of excess dietary zinc on pancreatic exocrine function in the chick. Jour. Nutr. 118 681-689. [Pg.736]

Wolfe, J.L., R.J. Esher, K.M. Robinson, and J.D. Yarbrough. 1979. Lethal and reproductive effects of dietary mirex and DDT on old-field mice, Peromyscus polionotus. Bull. Environ. Contam. Toxicol. 21 397-402. Wood, P.B., C. Vivarette, L. Goodrich, M. Pokras, and C. Tibbott. 1996. Environmental contaminant levels in sharp-shinned hawks from the eastern United States. Jour. Raptor Res. 30 136-144. [Pg.1158]

Shipp, E.B., J.C. Restum, S.J. Bursian, R.J. Aulerich, and W.G. Helferich. 1998b. Multigenerational study of the effects of consumption of PCB-contaminated carp from Saginaw Bay, Lake Huron, on mink. 3. Estrogen receptor and progesterone receptor concentrations, and potential correlation with dietary PCB consumption. Jour. Toxicol. Environ. Health 54A 403-420. [Pg.1337]

Hoffman, D.J., CJ. Sanderson, LJ. LeCaptain, E. Cromartie, and G.W. Pendleton. 1991b. Interactive effects of boron, selenium, and dietary protein on survival, growth, and physiology in mallard ducklings. Arch. Environ. Contamin. Toxicol. 20 288-294. [Pg.1628]

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Contaminants effects

Contamination effect

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