Conjugated linoleic acid commercial availability

Yurawecz, M.R, N. Sehat, M.M. Mossoba, JA.G. Roach, J.K.G. Kramer, and Y. Ku.. Variations in Isomer Distribution in Commercially Available Conjugated Linoleic Acid, Fett-IMdlOh 277-282 (1999). 

Variations in Isomer Distribution in Commercially Available Conjugated Linoleic Acid. Fett/Litid lOh 277-282 (1999). 

Several papers have reported the preparation of CLA isomers labeled with carbon isotopes. In aU cases, the labeled carbon atom was located on the carboxylic position. It should also be pointed out that recent preparations of unlabeled (9Z,llE) and (10 ,12 conjugated linoleic acid isomers in their highly purified form were accomplished by alkaline isomerization of (9Z,12Z) linoleic acid followed by selective lipase-catalyzed fractionation (16-18). These procedures may be used for the production of labeled (9Z,llE) and (10E,12Z) CLA because analogs of hnoleic acid labeled with carbon 13 or carbon 14 are commercially available. 

Yurawecz, M.P., Sehat, N., Mossoba, M.M., Roach, J.A.G., Kramer, J.K.G., and Ku, Y., Variations in isomer distribution in commercially available conjugated linoleic acid,... 

Lipoxygenase-Catalyzed Oxidations. Lipoxygenase-1 catalyzes the incorporation of dioxygen into polyunsaturated fatty acids possessing a l(Z),4(Z)-pentadienyi moiety to yield ( ),(Z)-conjugated hydroperoxides. A highly active preparation of the enzyme from soybean is commercially available in purified form. From a practical standpoint it is important to mention that the substrate does not need to be in solution to undergo the oxidation. Indeed, the treatment of 28 g/L of linoleic acid [60-33-3] with 2 mg of the enzyme results in (135)-hydroperoxide of linoleic acid in 80% yield... 

Commercially available soybean oils have a triglyceride structure. Oleic (C18 l), linoleic (C18 2) and linolenic acid (C18 3) are the primary fatty acid components of soybean oils (Table I). Regular soybean oil (SOY) has approximately 4.5 C=C bonds per triglyceride, while low saturation soybean oil (LSS) has approximately 5.1 C=C bonds. LSS oil is a commercially available soybean oil with considerably more linoleic acid 4). The fatty acid side chains in these two soybean oils are non- conjugated. Conjugated LSS oil (CLS) has been prepared in our laboratories from LSS by Rh-catalyzed isomerization 36). 

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