Condylox

Pure podophyllotoxin (podofilox) is approved for use as a 0.5% podophyllotoxin preparation (Condylox) for application by the patient in the treatment of genital condylomas. The low concentration of podofilox significantly reduces the potential for systemic toxicity. Most men with penile warts may be treated with less than 70 n-L per application. At this dose, podofilox is not routinely detected in the serum. Treatment is self administered in treatment cycles of twice-daily application for 3 consecutive days followed by a 4-day drug-free period. Local adverse effects include inflammation, erosions, burning pain, and itching. 

Condylox is the brand name of podofilox, an antimitotic drug that can be chemically synthesized or purified from the plant families Coniferae and Berberidaceae (e.g., species of Juniperus and Podophyllum). Condylox 0.5% solu-... 

Antimitotic Podofilox Condylox Hydroxypropyl cellulose Hydroalcoholic... 

Podophyllin (podophyllum resin) is a mixture of chemicals from the plant Podophyllum peltatum (mandrake or May apple). The major constituent of the resin is podophyllotoxin (podofilox). It binds to microtubules and causes mitotic arrest in metaphase. Podophyllum resin (10 0%) is applied and left in place for 2-6 hours weekly for the treatment of anogenital warts. Irritation and ulcerative local reactions are the major side effects. It should not be used in the mouth or during pregnancy. Podofilox (CONDYLOX, others) is available as a 0.5% solution for application twice daily for 3 consecutive days. Weekly cycles may be repeated. 

Trade Names Condyline, Condylox, Martec, Warticon Use Antiviral... 

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