Common template

The alternative approach is to use the computational equivalent of a chemical reaction, or reaction transform. Here, one does not need to define a common template or to generate sets of clipped reagents. Rather, the library can be enumerated using as input the initial reagent structures and the chemical transforms required to operate upon them. In this... 

These studies resulted in the synthesis of thirteen analogs that shared a common template. 

The most common template syntheses have been for macrocycles containing the donor atoms in the ratio of 2 2, e.g., reaction of the Ni(II) complexes (LXXXV), formed by condensation of oc-diketones with /i-mercaptoamines in the presence of Ni(II) ions, with a,a -dibromo-o-xylene affords LXXXVI through a kinetic template effect (see Section II,A) (136-138). Reaction with acetone links the coordinated amine groups of dithiodiamine to form the macrocycle complex LXXXVII (23). 

An effective template metal ion binds strongly to the donor atoms of the macrocycle or its precursors, e.g., K+ is the most common template for synthesis of crown ethers and forms definite complexes with a wide variety of crown ethers. 

While the films formed by using common templates such as Brij56 show a strong contraction of the structure upon calcination because of the thermally driven network condensation, loss of the organic template, and/or phase transitions, the PDMS-6-PEO-templated films revealed no contraction of the structure with the c(-spacing for the calcined films remaining unchanged. 

INERIS (2007) Implementation of requirements for priority substances within the context of the Water Framework Directive, common template for data collection . Final version 20 March 2007. 

For this purpose the Commission developed a common template for regular reporting of chemical monitoring data in WISE. The template is proposed as a common template for the various data collection exercises on chemical substances to be carried out by EC DG ENV for the WED, and by EEA for the preparation of the State of the Environment (SOE) report. 

In line with the above, a nnmber of QA/QC metadata were selected in the common template for data reporting at EU level nnder the WED, but not all of them are mandatory (i.e. they are not Category 1 data), as can be seen in Table 9.1.1. 

The most common template synthesis of macrocycles containing both sulfur and nitrogen atoms is the condensation of a-diketones (or acetone), 3-mer-... 

The radical ring-opening elimination polymerization of 4-methylene-l,3-dioxolane stimulated us to construct a novel template polymerization (3). The concept is that polymers bear polymers. Polymer-supported monomer, which had a structure of 2,2-dipheny 1-4-methylene-1,3-dioxolane, reacted with radical species to afford polyketone and copolymer of styrene with vinylbenzophenone as newborn polymer and template, respectively (Figure 12). These polymers were easily separated by fractional precipitation without any particular chemical treatment after polymerization. On the other hand, common template polymerization requires annoying procedures for the separation of obtained polymers form template. On this point, our novel template polymerization system differs from conventional template polymerization. 

Basically 5-HT selective uptake inhibitors like MDL28618, femoxetine (fig. 5, table 6) and its dose structural analog paroxetine (table 6) can all be considered rigidified phenoxypropamine derivatives that may interact with the same recognition site at the 5-HT transporter. Fluoxetine and its rigidified analogs all seem to fit a common template (fig. 5). 

Figure 4.15 The sizes of common clathrate hydrate guests and the clathrate hydrate structures that they commonly template.

Inclusion Teams that have a common template for all meetings find recording information and sharing it easier to handle (see, CD, Chapter 4 Example 5). This template should he filled in and actions agreed as the meeting progresses this form could then be photocopied and circulated... 

Currently, microelectronics relies on bulk sihca as an important dielectric material that is often used as an insulating template for further reactivity. On the nanoscale, sUica can be synthesized by polymerizing silicic acid in an aqueous system, or through hydrolysis and condensation of silicon alkoxides in the Stober synthesis [51]. The mechanism of these two methods is unique. The first method is dominated by monomers and tetra-functionalized species, such that the resultant sihcate sols are uniform, which means that they are fully hydrolyzed and grow by monomer addition. In contrast, for the second method, di- and tri-functionalized species are dominant for alkoxides. Regardless of the synthesis used, these particles induce a fractal interior with minimal morphological control due to their common template, ammonium hydroxide [51]. 

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