Combinatorial chemistry high throughput screening

Woodyer, R., van der Donk, W.A. and Zhao, H.M. (2006) Optimizing a biocatalyst for improved NAD(P)H regeneration directed evolution of phosphite dehydrogenase. Combinatorial Chemistry High Throughput Screening, 9, 237-245. 

Burke, T.J., Loniello, K.R., Beebe, J.A. and Ervin, K.M. (2003) Development and application of fluorescence polarization assays in drug discovery. Combinatorial Chemistry High Throughput Screening, 6, 183-194. 

Carlson, T.J. and Eisher, M.B. (2008) Recent advances in high throughput screening for ADME properties. Combinatorial Chemistry High Throughput Screen, 11, 258—264. 

New scientific approaches, e.g. combinatorial chemistry, high-throughput screening, in silico models, pharmaco-genomics and pharmaco-proteomics offered new possibilities. 

Zhang, W. 2007. Fluorous-enhanced multicomponent reactions for making drug-like library scaffolds. Combinatorial Chemistry High Throughput Screening, 10 219-29. 

A. Schuller, U. Fechner, S. Renner, L. Franke, L. Weber and G. Schneider, Combinatorial chemistry high throughput screening, 2006, 9, 359-364. 

An increasing interest of the scientific community in recent years has been shown in the fields of combinatorial chemistry, high-throughput screening, - substructural analysis, and -+ similarity searching, for which several similarity/diversity approaches have been proposed mainly based on - substructure descriptors such as -> molecular fingerprints, which are particularly suitable for informatic treatment. 

Tombelli, S. and Mascini, M. (2010) Aptamers biosensors for pharmaceutical compounds. Combinatorial Chemistry High Throughput Screening, 13 (7), 641-549. 

DE Bergbreiter, JG Franchina, BL Case, LK Williams, JD Frels, N. Koshti. Combinatorial Chemistry High Throughput Screening ) 153-164, 2000. 

Some recent papers on directed evolution include a) Farinas, E. T. Combinatorial Chemistry High Throughput Screening 2006, 9(4), 321. 

A site worth watching for the future is http //www. combichemlab.com. This academic-oriented site is intended to provide free on-line information in the areas of combinatorial chemistry, high-throughput screening, and other related topics. Refreshingly, fhese days, there are no specials, offers or advertisements of any kind. 

P. Englebietme, A. van Hoonacker, M. Verhas, and N. G. Khlebtsov, Combinatorial Chemistry High Throughput Screening 6, 777 (2003). 

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