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Collapsin response mediator proteins

Two effects relevant to the mechanism of action of lacosamide as an antiseizure drug have been described. Lacosamide enhances slow inactivation of voltage-gated Na+ channels. It also binds to the collapsin-response mediator protein, CRMP-2, thereby blocking the effect of neurotrophic factors such as BDNF and NT3 on axonal and dendritic growth. [Pg.520]

Charrier E, Reibel S, Rogemond V, Aguera M, Thomasset N, Honnorat J. Collapsin response mediator proteins (CRMPs) Involvement in nervous system development and adult neurodegenerative disorders. Mol Neurobiol 2003 28(l) 51-64. [Pg.173]

Collapsin response mediator proteins (CRMPs) include a family of hve members that are involved in... [Pg.325]

Meyronet D, Massoma P, Thivolet F, et al. Extensive expression of a collapsin response mediation protein 5 (CRMP5) is a specific marker of high grade lung NE carcinoma. Am J Surg Pathol. 2008 32 1699-1708. [Pg.337]

Duplan, L., N. Bernard, W. Casseron et al. Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SODl mice and can trigger motoneuron axonal degeneration and ceU death. 30(2), 2010 785-96. [Pg.354]

Gu, Y, and Y. Ihara. Evidence that collapsin response mediator protein-2 is involved in the dynamics of microtubules. 275(24), 2000 17917-20. [Pg.355]

Weidemann W, Stelzl U, Lisewski U et al. (2006) The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNB), the key enzyme of sialic acid biosynthesis. FEBS Lett 580, 6649-6654. [Pg.189]

Collapsin response mediator protein 1, promyelocytic leukemia zinc-finger protein, and a-actinin 1 new molecular partners of GNE/MNK... [Pg.202]


See other pages where Collapsin response mediator proteins is mentioned: [Pg.510]    [Pg.253]    [Pg.149]    [Pg.291]    [Pg.415]    [Pg.561]    [Pg.220]    [Pg.343]    [Pg.350]    [Pg.181]    [Pg.510]    [Pg.253]    [Pg.149]    [Pg.291]    [Pg.415]    [Pg.561]    [Pg.220]    [Pg.343]    [Pg.350]    [Pg.181]   
See also in sourсe #XX -- [ Pg.202 ]




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Collapsin response mediator protein CRMP)

Collapsin response mediator proteins CRMPs)

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