Collagen fibrils structure

Holmes, D. F., Gilpin, C. J., Baldock, C., Ziese, U., Koster, A. J., and Kadler, K. E. (2001). Corneal collagen fibril structure in three dimensions Structural insights... 

Mineralization takes place in intimate association with the collagen framework, as well as in matrix vesicles that bud off the odontoblast processes. The very first dentin to mineralize (mantle dentin) contains a relatively large proportion of matrix vesicle derived mineral [31], whereas in the bulk of the dentin, most of the mineral is associated with collagen. The collagen fibril structure is therefore the key to understanding dentin structure and mineralization. Its main features are schematically depicted in Fig. 1.7d. We assume below that the basic characteristics of dentin collagen mineralization are the same as those for bone. 

One of the important facts regarding collagen fibril structure disclosed by electron optical studies is that the periodic band-interband patterns are polarized (193). In other words, as can be seen in Fig. 21, the fibrils possess no cross sectional planes of symmetry each has head and tail directions which are distinguishable. 

Chakravarti, S. Petroll, W.M. Hassell. J.R. Jester, J.V. Lass. J.H. Paul, J. Birk, D.E. Comeal opacity in lumican-null mice Defects in collagen fibril structure and packing in the posterior stroma. Invest. Ophthalmol. Vis. Sci. 2000, 41 (1 1), 3365-3373. 

Collagen fibril-associated small proteoglycans of mammalian origin, structure of, 49, 239-261... 

Collagen sponges with microporous structures from tilapia were fabricated reconstituted collagen fibrils using freeze-drying and cross-linked by DHT treatment or additional treatment with WSC treatment. The pellet implantation tests into the paravertebral muscle of rabbits demonstrated that tilapia collagen caused rare inflammatory responses at 1- and... 

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