Cobalt edetate

Treatment — Patients should be decontaminated immediately prior to treatment using the decontamination method presented in Section 7.3.3. The Lilly Cyanide Antidote Kit contains amyl nitrite, sodium nitrite, and sodium thiosulfate. Dimeth-ylaminophenol, cobalt-edetate, or vitamin B12a are alternative antidotes for cyanide poisoning.5... 

Flushed skin Dimethylaminophenol, cobalt-edetate, or vitamin B12a ate... 

Dicobalt edetate. Cobalt forms stable, nontoxic complexes with cyanide. It is toxic (especially if the wrong diagnosis is made and no cyanide is present), causing hypertension, tachycardia and chest pain consequent cobalt poisoning is treated by giving sodium calcium edetate and i.v. glucose. 

Note A number of salts of EDTA are available with uses identical or similar to the acid. The USP salts are called edetates (calcium disodium, disodium edetates) others are usually abbreviated to EDTA (tetrasodium, trisodium EDTA). Other salts, known chiefly under trademark names, are the sodium ferric, dihydrogen ferrous and arange of disodium salts with magnesium, divalent cobalt, manganese, copper, zinc, and nickel. 

Direct complex and capture agents Cobalt compounds Dicobalt edetate Cobalt histidine Cobalt chloride Cobalt acetate Sodium cobaltinitrite Cobamide Hydroxocobalamin ... 

B. Treatment. Successful treatment for acute cyanide poisoning depends upon rapid fixation of the cyanide ion, either by methemoglobin (metHB) formation or by fixation with cobalt compounds. Drug treatments include, compounds producing Methemoglobin, Hydroxyocobalamin, and Dicobalt edetate. Any casualty who is fully conscious and breathing... 

Figure 23 HPTLC-FTIR transmission spectra (A) and chromatogram (B) of cobalt(IID-EDTA (edetic acid) complex AMD (automated multiple development) chamber (CAMAG) with ammoniacal methanol-dichloromethane solvent gradient.

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