Coatings antimicrobial peptides

Rapsch and co-workers have discussed the antimicrobial activities of different peptides [48b]. They developed a rapid and efficient screening procedure to identify and investigate which biologically active peptides, in an immobilised state, could produce an effective antimicrobial surface coating. In addition to this, an antimicrobial surface coating of peptides exhibited no cytotoxic activity against a eukaryotic cell line (Figure 2.6). 

Cado, G., Aslam, R., Seon, L., Gamier, T., Fabre, R., Parat, A., et al., 2013. Self-defensive biomaterial coating against bacteria and yeasts polysaccharide multilayer film with embedded antimicrobial peptide. Adv. Fund. Mater. 23, 4801-4809. http //dx.doi.org/10.1002/ adfm.201300416. 

Kazemzadeh-Narbat, M., Lai, B.F.L., Ding, C., Kizhakkedathu, J.N., Hancock, R.E.W, Wang, R., 2013. Multilayered coating on titanium for controlled release of antimicrobial peptides for the prevention of implant-associated infections. Biomaterials 34,5969-5977. http //dx.doi. org/10.1016/j.biomaterials.2013.04.036. 

Rapsch, K., Bier, F.F., Tadros, M., von Nickisch-Rosenegk, M., 2014. Identification of antimicrobial peptides and immobilization strategy suitable for a covalent surface coating with biocompatible properties. Bioconjug. Chem. 25, 308-319. http //dx.doi.org/10.1021/ bc4004469. 

Anticoagulants, e.g., heparin and hirudin, antimicrobials, cell adhesion peptides, cell adhesion proteins, negative surface charge plasma polymerized coating, thrombolytics Tissue Adhesives... 

Muszanska, A.K., Rochford, E.T.J., Gruszka, A., Bastian, A.A., Busscher, H. J., Norde, W., et al., 2014. Antiadhesive polymer brush coating functionalized with antimicrobial and RGD peptides to reduce biofilm formation and enhance tissue integration. Biomacromolecules 15, 2019-2026. http //dx.doi.org/10.1021/bm500168s. 

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