Clostridium Homologies

Rafii F, Smith DB, Benson RW, Cemiglia CE (1992) Immunological homology among azoreductases from Clostridium and Eubacterium strains isolated from human intestinal microflora. J Basic Microbiol 32 99-105... 

Marsh, E. N. G., and Holloway, D. E., 1992, Cloning and sequencing of glutamate mutase component S from Clostridium tetanomorphum. Homologies with other cobalamin-dependent enzymes, FEBS Lett. 310 167nl70. 

Eichel-Streiber Cv, Sauerborn M (1990) Clostridium difficile toxin A carries a C-terminal repetitive structure homologous to the carbohydrate binding region of streptococcal glycosyltransferases. In Gene, 96 107—ll3. 

Eichel-Streiber Cv, Laufenberg-Feldmann R, Sartingen S, ef al. (1990) Cloning of Clostridium difficile toxin B gene and demonstration of high N-terminal homology between toxin A and B. In Med. Microbiol. Immunol. 179 271 —279. 

Green GA, Schue V, Monteil H (1995) Cloning and characterization of the cytotoxin L-encoding gene of Clostridium sordellii homology with Clostridium difficile cytotoxin B. In Gene, 161 57-61. 

Hofmann F, Herrmann A, Habermann E, etal. (1995) Sequencing and analysis of the gene encoding the alpha-toxin of Clostridium novyi proves its homology to toxins A and B of Clostridium difficile. In A4o/ Gen Genet, 247 670—679. 

The CoMFA methodology was also used to describe nonlinear lipophilicity-activity relationships, c.g. the inhibitory activities of quaternary alkylbenzyl-dimethylammonium compounds vs. Clostridium welchii (eqs. 206—208) [1025], other antibacterial and hemolytic activities [1026, 1027], and toxic activities of alkanes in mice (eqs. 209-211) [1026] the results of classical QSAR studies (eqs. 206, 207, 209, and 210) [23, 440] were compared with the corresponding CoMFA results (eqs. 208 and 211) [1025-1027] only homologous series of compounds were investigated. 

Mermelstein LD, Welker NE, Bennett GN, Papoutsakis FT. (1992). Expression of cloned homologous fermentative genes in Clostridium acetobutylicum ATCC 824. Bio-Technology, 10,190-195. 

---