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Clinical pathway mapping

Critical pathways, also known as clinical pathways or care maps, are tools of patient care management that are created by multidisciplinary teams, which are intended to lead to the most desirable patient outcome in the most desirable time frame. These programs prespecify what procedures, lab tests, medications, and dietary and exercise needs a patient should receive during a hospitalization for a specific time. There exists evidence that programs that focus on knee-replacement therapy and community-acquired pneumonia are... [Pg.190]

Another approach is the inhibition of the TNF-converting enzyme (TACE), which converts proTNF into its mature, proinflammatory form. Also, numerous inhibitors of P38 and Erk-MAP kinases have been synthesized and some have reached the clinical trial stage. MAP-p38 kinase occupies a central role in the signaling network responsible for the up-regulation of proinflammatory cytokines like interleukin 1 and TNFa. The pathway of Erk-MAP kinase is often up-regulated in human tumors and as such represents an attractive target for the development of anticancer drugs. ... [Pg.98]


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Pathway maps

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