Clinical incidents

Most drug labels report incidence for ADRs in categories such as common, frequent, infrequent, rare, or not known. These clinical incidence data were entered into the BioPrint database in text-based groups defined below. Although some drug labels report ADRs with continuous clinical incidence data from 0% to 100%, this data was also entered according to the text-based bins ... 

Sekine, Y., Rikihisa, T, Ogata, H., Echizen, H., and Arakawa, Y. (1999) Correlations between in vitro activity of antipsychotics to various central neurotransmitter receptors and clinical incidence of their adverse drug reactions. Eur J Clin Pharmacol 55 583— 587. 

Specific drug-induced renal structural-functional alterations constitute the remainder of this discussion under the seven broad headings listed in Table 46-1. The general orientation of these topics is in order of decreasing clinical incidence. Pathophysiologic mechanisms of nephrotoxicity will be emphasized, in addition to clinical findings, prevention, and management. 

Taylor-Adams S, Vincent C. Systems analysis of clinical incidents. The London Protocol. [Online], [cited Jun 2015. Available from http //wwwLimperial.ac.uk/cpssq/cpssq publica-tions/resources tools/the london protocol/. 

Reporting and learning systems 83 Table 5.2 Examples of designated clinical incidents to be reported... 

Systems analysis of clinical incidents the London Protocol... 

Fetter J, Bobeldyk GL, Engman EJ. The clinical incidence and significance of myopotential sensing with unipolar pacemakers. Pacing Clin Electrophysiol 1984 7 871-881. 

EUingson K, et al Sustained reduction in the clinical incidence of methicillin-resistant Staphylococcus aureus colonization or infection associated with a multifaceted infection control intervention. Infect Control Hosp Epidemiol 2011 32 1-8. 

Vincent, C., Taylor-Adams, S., Chapman, E. J., Hewett, D., Prior, S., Strange, P. and Tizzard, A. (2000). How to investigate and analyse clinical incidents Clinical Risk Unit and Association of Litigation and Risk Management protocol. British Medical Journal, 320, 777-781. 

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