Click step-growth polymerization

Alkene-functionalized linear polymers, such as the polyether-thioether described in Figure 3.9, was prepared by thiol-ene click step-growth polymerization using a fast, efficient, and green approach for the synthesis of macromonomers with a variety of functionalities. 

L. Billiet, D. Fournier, R Du Prez, Step-growth polymerization and click chemistry the oldest polymers rejuvenated. Polymer 50 (July 31, 2009) 3877-3886. 

Hecht and co-workers developed another class of polymers based on allgme-azide click chemistry. The synthesis of these new polymers was an A2-I-B2 step-growth polymerization, with A2 corresponding to the 2,6-diethynylpyridine monomer and B2 to the 3,5-diazidohenzoate monomer that reacted together under Cu-catalyzed 1,3-dipolar cycloaddition reaction conditions (Figure 5.22). 

In a typical procedure, the thiol-epoxy click reaction near quantitative yields can be employed as a polymerization reaction for preparing linear polymer chains substituted with free hydroxyl groups. Khan et al. [16] reported that the linear polymer can be easily constructed by step-growth polymerization of the commercially available diepoxide (AA-type) and bis-sulfur (BB-type) monomers using lithium hydroxide (base catalysts) as the polymerization catalyst. (Figure 8.3)... 

Tsarevsky, N.V. Sumerlin, B.S. Matyjaszewski, K. Step-growth click coupling of telechelic polymers prepared by atom transfer radical polymerization. Macromolecules 2005, 38 (9), 3558-3561. 

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