Clenbuterol immunoaffinity chromatography

W. Haasnoot, M. E. Ploum, R. J. A. Paulussen, R. Schilt and F. A. Huf, Rapid determination of clenbuterol residues in urine by high perfoi mance liquid cliromatography with on-line automated sample processing using immunoaffinity chromatography , 7. Chromatogr. 519 323-335 (1990). 

Examples exist of different types of immunobased technology being interfaced to produce an effective analytical system. In a variety of recent methods, immunoaffinity chromatography has been employed for purification, chemiluminescence enzyme immunoassay has been used for quantification of salbutamol and clenbuterol in tissue and plasma from calves and pigs (122), clenbuterol in cattle hair (123), and monensin in chicken tissues (124). In these methods, quantification at sub-ppb levels has been demonstrated. 

RJH Picket, MJ Sauer. Determination of clenbuterol in bovine urine by enzyme immunoassay following concentration and clean-up by immunoaffinity chromatography. Anal Chim Acta 275 268, 1993. 

Lawrence, J.F. Menard, C. Determination of clenbuterol in beef-liver and muscle-tissue using immunoaffinity chromatographic cleanup and liquid-chromatography with ultraviolet absorbency detection. J. Chromatogr. 

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