Class III peroxidase

Cosio C. Dunand C. (2009) Specific function of individual class III peroxidase genes // J. Exp. Botany. V. 60. P. 391-408. 

Cosio C. Vuillemin L. De Meyer M. Kevers C. Penel C. Dunand C. (2009) An anionic class III peroxidases from zuccini may regulate hypocotyl elongation through its auxin oxidase activity / / Planta. V. 229. P. 823-836. 

Profiling of wheat class III peroxidases genes derived from powdery mildew-attacked epidermis reveals distinct sequence-associated expression patterns / / Molecular Plant-Microbe Interactions. V. 18. P. 730-741. 

Simonetti E. Veronico P. Melillo M. T. Delibes A. Andres M.F. Lopez-Brana I. (2009) Analysis of class III peroxidase genes expressed in roots of resistant and susceptible wheat lines infected by Heterodera avenae / / Mol. Plant-Microbe Interact. V. 22. P. 1081-1092. 

M. Duroux L. (2002) Structural diversity and transcription of class III peroxidase POs from Arabidopsis thaliana / / Europ. J. Biochem. V. 269. P. 6063-6081. 

Pierattelli R, L Banci, NA Eady, J Bodiguel, JN Jones, PCE Moody, EL Raven, B Jamart-Gregoire, K A Brown (2004) Enzyme-catalyzed mechanism of isoniazide activation in Class I and Class III peroxidases. J Biol Chem 279 39000-39009. 

Welinder KG, Justensen AF, Kjaersgard IV et al (2002) Structural diversity and transcription of Class III peroxidases from Arabidopsis thaliana. Eur J Biochem 269 6063-6081... 

Passardi F, Longet D, Penel C et al (2004) The Class III peroxidase multigenic family in rice and its evolution in land plants. Phytochemistry 65 1879-1893... 

Kvaratskhelia, M., Winkel, C., Naldrett, M. T., and Thorneley, R. N. F., 1999, A novel high activity cationic ascorbate from tea (Camellia sinensis)6a class III peroxidase wilh unusual subslrale specificity, J. Plant Physiol. 154 273n282. 

These various structures together with the conserved structures around the 5-edge heme suggests a common pattern of binding between class III peroxidases and aromatic substrates. Such common aromatic contacts have also been observed in the complexes between class II peroxidase ARP and BHA, and salicylhydroxamic acid, respectively. ... 

Glycosylation is one of the main factors determining the unusual thermal stability of class III peroxidases [24], since deglycosylated forms have frequently been observed to exhibit reduced thermal stability [25], Partial deglycosylation has also been described as causing a change in the kinetic constants of avocado peroxidase and as favoring activation by Ca [25],... 

Class III peroxidases isolated from C. roseus are capable of oxidizing ajmalicine (XLVIII) to serpentine (LV) [150]. The kz value of C. roseus peroxidase for this reaction is about 0.0011 pM s at pH 6.0 [74]. This constitutes a unique example in peroxidase-catalyzed metabolic reactions since it involves the aromatization of a N-heterocyclic ring (Scheme XXV). 

The plant peroxidase superfamily consists of evolutionarily related heme peroxidases from bacteria, fungi, and plants (28). The superfamily can be divided into three classes based on amino acid sequence (28). CCP and plant cytosolic ascorbate peroxidase fall into class I, and the main role of peroxidases in this class appears to be the removal of H2O2. Class II comprises the extracellular peroxidases such as lignindegrading LIP and MnP CIP and ARP also belong to class II, but their function is unknown. Class III peroxidases include the classical plant secretory peroxidases such as HRP and its isoenzymes, and barley peroxidase. 

Class III peroxidases have been the subject of numerous studies [10] and applications [11], since their extraordinary catalytic properties make them a valuable catalytic tool in the plant cell chemical factory, and in organic synthesis. In fact, class III peroxidases, together with other oxidative enzymes, such as cytochrome P450s and oxygenases [12], appear to be the main driving force in the evolution of plant metabolic pathways because individual enzymes can typically accept multiple substrates and form several products. This metabolic plasticity of class III peroxidases, paradoxically, has frequently led to misunderstanding of its vital function in the plant cell biochemical factory. 

Introduction Class I Peroxidases Class II Peroxidases Class III Peroxidase... 

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