CJun N-terminal kinase

Stress-activated PK/cJun N-terminal kinase (SAPK/JNK)... [Pg.828]

Overexpression of FASN in tumor cells is induced at the transcriptional level by receptor tyrosine kinase (RTK)-stimulation of Ras and Akt (Fig. 7.2B). Keratinocyte growth factor (KGF) can induce the Akt- and cJun N-terminal kinase (JNK)-dependent expression of FASN in pulmonary cancer cells (Chang et ah, 2005). Epidermal growth factor (EGF) has also been shown to increase FASN in prostate cancer cells (Swinnen et ah, 2000a). [Pg.178]

Receptor-like protein tyrosine phosphatases Receptor tyrosine kinases Stress-activated PK/cJun N-terminal kinase SAPK/ERK kinase 1 Src homology domain 2 Transforming growth factor-(3 Tumour necrosis factor 12-O-tetradecanoylphorbol-13-acetate Tyrosine specific phosphatases... [Pg.885]

IRS-1 insulin receptor substrate-1 JNK cJun N-terminal protein kinase... [Pg.201]