CIP method

Yabe, T. Interface Capturing and Universal Solution of Solid, Liquid and Gas by CIP Method . Proceedings of the High-Performance Computing of Multi-Phase Flow, Tokyo, July 18-19, 1997. 

For a WFI or highly purified water system, the SIP/CIP method is usually applied. In an SIP/CIP system, sterilization and/or cleaning take in place in situ or without dissembling the equipment. Consequently, the result of sterilization and/ or cleaning is confirmed by the process parameters previously validated. Based on process parameters and their ranges previously determined by the process validation, the SIP/CIP process can be confirmed whether or not it is completely sterilized and cleaned. This is a typical application of the concept of validation. 

Desalting of lysine-rich fermentation broths by monopolar ED appears to be much more rewarding. To mitigate anionic membranes sensitivity to fouling, Lee et al. (2002b, 2003) resorted to pulsed electric field with the halfwave power and suggested the use of pulse power as an effective CIP method during ED of fermentation media. 

Cleaning in place (CIP) can be defined as circulation of cleaning liquids through machines and other equipment in a cleaning circuit (84). This method of cleaning has replaced the older practice of stripping down valves and other difficult to clean equipment in many margarine factories. The CIP method is essentially the same as the method described above (85). 

For these structures the CIP method provides a formalism for exploring a ligand to determine the ligand of highest priority, second highest, third, etc. 

T. Yabe, F. Xiao and T. Utsumi, The Constrained Interpolation Profile (CIP) Methods for Multiphase Analysis, J. Comput. Phys., 169(2), 708-759 (2001). 

The effectiveness of cathodic protection can be accomphshed by monitoring the pipeline potential using the close interval potential survey (CIPS) method or by using direct current voltage gradient (DCVG) or IR coupon techniques. Also, physical and electrochemical methods can be used to estimate the corrosion rates of a cathodicaUy protected system. 

Alternative means for liquid discharge have been developed, largely from other centrifuge types, such as centripetal and skimmer pumps. Decanters have been fitted with discs to improve clarification performance, and sanitary performance has been improved by the development of clean-in-place (CIP) methods. 

The CIPS method is based on the connection of a thin, strong cable to the tested pipeline and making readings of the potential every 10-20 cm along the route of the pipeline against a portable reference electrode. The cable with a scale wound on a drum is used at the same time to measure the distance with an accuracy of 1%. Also, satellite localization can be used, giving the po-... 

Figure -20. Schematic diagram of testing insulation leakiness by the CIPS method. (From Global Cathodic protection Ltd.)...

The recovery of gold by the carbon-in-pulp (CIP) method utilizes the strong adsorption of [Au(CN)2 ] onto the surface of activated carbon in alkaline (pH >11) regimes (Adams Fleming 1989 Adams 1993). The same mechanisms can be utilized to adsorb contaminants from a water column. At the present time only experimental studies have been carried out (Hegenberger et al. 1987 McEnamey 1988 van der Merwe van Deventer 1988). The technique has also been applied to volatile and dense organic solvents (Pankow Cherry 1996). 

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