Cigarette smoke components

Bridges RB, Kraal JH, Huang L JT, et al. 1977. Effects of cigarette smoke components on in vitro chemotaxis of human polymorphonuclear leukocytes. Infec Immun 16 240-248. 

Jakab GJ. 1977. Adverse effect of a cigarette smoke component, acrolein, on pulmonary antibacterial defenses and on viral-bacterial interactions in the lung. Am Rev Respir Dis 115 33-38. 

Low ES, Low RB, Green GM. 1977. Correlated effects of cigarette smoke components on alveolar macrophage adenosine triphosphatase activity and phagocytosis. Am Rev Respir Dis 115 963-970. 

Rylander R. 1973. Toxicity of cigarette smoke components. Free lung cell response in acute exposures. Am Rev Resp Dis 108 1279-1282. 

While the minor contribution of B[a]P to the tumorige-nicity of CSC to mouse skin has been recognized since the mid-1950s (4353,4354), its presence in CSC has elicited continued interest since that time. Examination of the references to various smoke components reveals an interesting fact about B[a]P When all the cigarette smoke components are tabulated with regard to similar selection of references across the board, very few tobacco smoke components exceed B[a] P in the number of pertinent references available. Obviously, the smoke component discussed most in publications and presentations between the mid-1950s and 2005 was nicotine. Next was acetaldehyde, followed by B[a]P. 

In 1960, Van Duuren et al. (4027) reported the identification of several aza-arenes (dibenz[fl,/t]acridine, dibenz[a, ]acridine, dibenzo[c,g]carbazole) not only structurally similar to some of the known tumorigenic PAHs in CSC but also reported under certain conditions to be tumorigenic to mouse skin. Adding this class of tumorigenic cigarette smoke components to the assessment of the tumorigenicity of CSC failed to account for more than a few percent of the observed response. 

Rinkus and Legator (3157) listed numerous tobacco and cigarette smoke components as mutagenic in the Salmonella typhimurium system. Among these were the following volatile NNAs [excluding (NMOR)] known to occur in tobacco smoke NDMA, NDEA, NPYR, NDBA, NDPA, NMOR, NPIP. 

Artho, A.J. and R. Koch Characteristics of the olfactory properties of cigarette smoke components Anal. Tabac (SEITA) (1973) 37 3. 

Case, P.D. The build-up and decay of ambient cigarette smoke components 39th Tobacco Chemists Research Conference, Program Booklet and Abstracts, Vol. 39, Paper No. 46, 1985, p. 25. 

Irwin, W.D.E. Discussion of a study on the determination of mainstream and sidestream cigarette smoke components for cigarette of different tobacco types and a set of reference cigarettes Beitr. Tabakforsch. Int. 18 (1998) 115-118. 

Izawa, M., Y. Kobashi, C. Tokura, M. Motomatsu, and T. Fukaya Studies on tobacco smoke. Part IV. Fractionation of cigarette smoke components and some low boiling nitrogenous compounds Sci. Papers, Cent. Res. Inst., Japan Monopoly Corp 99 (1958) 60-65. 

Klus, H. Distribution of mainstream and sidestream cigarette smoke components Recent Adv. Tob. Sci. 16 (1990) 189-232. 

Borgerding Quantitative analysis of selected cigarette smoking components using gas chromatography diode array ultraviolet spectrophotometry 52nd Tobacco... 

Resnik, F.E., W.H. Danker, and F.L. Daylor Flavour evaluation of cigarette smoke components Proc. 3rd Internat. Tob. Sci. Cong., Salisbury, Rhodesia, 1963 (1964) 522-533. 

Sakuma, H., M. Kusama, S. Munakata, T. Ohsumi, and S. Sugawara The distribution of cigarette smoke components between mainstream and sidestream smoke. I. 

Quantitative changes of cigarette smoke components 3865b. 

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